Results 111 to 120 of about 848,438 (282)
Selfduality and Strongly Graded Rings
Let \(R\) be a ring graded by a finite group \(G\). The author proves that \(R\) has graded self-duality iff the smash product \(R\# G\) has self-duality iff \(R\) has self-duality. If \(R\) is strongly graded then \(R\) has self-duality iff its initial subring \(R_e\) has self-duality.
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
On Graded Strongly J_gr^Soc-2-Absorbing Submodules
Let $\mathfrakB$ be a graded commutative ring with unity, and let $\mathfrakW$ be a graded unital $\mathfrakB$-module. This study introduces and develops the concept of graded strongly $J_gr^Soc$-2-absorbing submodules, a natural extension of graded ...
Malak Alnimer, Khaldoun Al-Zoubi
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Density of Tree-Ring Grids in Western North America
The separating distance over which tree-ring chronologies are significantly correlated is investigated. Any chronology occuring within a radius of 161 km of another is estimated to contain at least half of the common variance occurring at zero separating
Cropper, John Philip, Fritts, Harold C.
core +3 more sources
On Graded Rings, II ($\mathbf{Z}^n$-graded rings)
GOTO, Shiro, WATANABE, Keiichi
openaire +3 more sources
Bimodules in Group Graded Rings
In this article we introduce the notion of a controlled group graded ring. Let $G$ be a group, with identity element $e$, and let $R=\oplus_{g\in G} R_g$ be a unital $G$-graded ring. We say that $R$ is $G$-controlled if there is a one-to-one correspondence between subsets of the group $G$ and (mutually non-isomorphic) $R_e$-bimodules in $R$, given by ...
openaire +4 more sources
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source

