Results 101 to 110 of about 30,010 (264)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Derived equivalences of upper-triangular ring spectra via lax limits
Comptes Rendus. MathématiqueWe extend a theorem of Ladkani concerning derived equivalences between upper-triangular matrix rings to ring spectra. Our result also extends an analogous theorem of Maycock for differential graded algebras.
Jasso, Gustavo
doaj +1 more source
International Journal of Mathematics and Mathematical Sciences, 2006 We discuss the calculation of integral cohomology ring of LG/T and ΩG. First we describe the root system and Weyl group of LG, then we give some homotopy equivalences on the loop groups and homogeneous spaces, and calculate the cohomology ring structures
Cenap Özel, Erol Yilmaz
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Some Properties of Serre Subcategories in the Graded Local Cohomology Modules
Journal of Mathematics, 2017 Let R=⊕n≥0Rn be a standard homogeneous Noetherian ring with local base ring (R0,m0) and let M be a finitely generated graded R-module. Let HR+i(M) be the ith local cohomology module of M with respect to R+=⊕n>0Rn.
Feysal Hassani, Rasul Rasuli
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Control subgroups and birational extensions of graded rings
International Journal of Mathematics and Mathematical Sciences, 1999 In this paper, we establish the relation between the concept of control subgroups and the class of graded birational algebras. Actually, we prove that if R=⊕σ∈GRσ is a strongly G-graded ring and H⊲G, then the embedding i:R(H)↪R, where R(H)=⊕σ∈HRσ, is a ...
Salah El Din S. Hussein
doaj +1 more source
Selfduality and Strongly Graded Rings
Journal of Algebra, 1997 Let \(R\) be a ring graded by a finite group \(G\). The author proves that \(R\) has graded self-duality iff the smash product \(R\# G\) has self-duality iff \(R\) has self-duality. If \(R\) is strongly graded then \(R\) has self-duality iff its initial subring \(R_e\) has self-duality.
openaire +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source