Results 111 to 120 of about 2,146,103 (291)

Fabrication of an Organic-Inorganic Hybrid Hard Coat with a Gradient Structure Controlled by Photoirradiation. [PDF]

ACS Appl Mater Interfaces, 2023
Shirai Y, Sasaki A, Sato S, Aoki D, Arimitsu K.   +4 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Unbiased and efficient sampling of timeseries reveals redundancy of brain network and gradient structure. [PDF]

Neuroimage, 2023
Nanda A, Rubinov M.
europepmc   +1 more source

Patterns in a Smoluchowski Equation

, 2006
We analyze the dynamics of concentrated polymer solutions modeled by a 2D Smoluchowski equation. We describe the long time behavior of the polymer suspensions in a fluid.
Zarnescu, Arghir
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Preparation and Characterization of Biomimetic Functional Scaffold with Gradient Structure for Osteochondral Defect Repair. [PDF]

Bioengineering (Basel), 2023
Chen L, Wei L, Su X, Qin L, Xu Z, Huang X, Chen H, Hu N.   +7 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Gradient Structure of the Transfer Layer in Friction Stir Welding Joints. [PDF]

Materials (Basel), 2022
Eliseev A, Osipovich K, Fortuna S.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Study on Microstructure Evolution Mechanism of Gradient Structure Surface of AA7075 Aluminum Alloy by Ultrasonic Surface Rolling Treatment. [PDF]

Materials (Basel), 2023
Fu L, Li X, Lin L, Wang Z, Zhang Y, Luo Y, Yan S, He C, Wang Q.   +8 more
europepmc   +1 more source