Results 131 to 140 of about 1,429,141 (363)
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Expressões de análise de sensibilidade em problemas elásticos [PDF]
Neste trabalho, desenvolvem-se as expressões continuas de análise de sensibilidade em problemas elásticos lineares. Consideram-se variáveis relacionadas a parâmetros discretos e de forma do problema estrutural. Aspectos da implementação das classes em C +
Bittencourt, Marco Lucio +1 more
core +1 more source
Byzantine-Resilient Gradient Coding Through Local Gradient Computations
We consider gradient coding in the presence of an adversary controlling so-called malicious workers trying to corrupt the computations. Previous works propose the use of MDS codes to treat the responses from malicious workers as errors and correct them using the error-correction properties of the code.
Christoph Hofmeister +3 more
openaire +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Diseño óptimo de celosías planas con criterios de estado límite último [PDF]
En este trabajo se presenta una metodología de cálculo óptimo de estructuras articuladas planas qne permite obtener la forma geométrica y las secciones más convenientes de la estructura.
Andreu, Antoni, Gil, Lluís
core +2 more sources
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Investigou-se a influência da estação do ano sobre as características termorreguladoras e de pelame bem como os gradientes térmicos em novilhas da raça Nelore.
Álvaro Moriya Shiota +5 more
doaj
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Solución simultánea de las ecuaciones gobernanates del problema termo-elastohidrodinámico de contacto lineal [PDF]
Un modelo unidimensional del problema termo-elastohidrodinámico de contacto lineal se resuelve numéricamente usando el método de elementos finitos. El sistema de ecuaciones resultante es fuertemente no lineal y se resuelve en forma simultánea mediante ...
Di Paolo, José
core

