Results 131 to 140 of about 1,429,141 (363)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Expressões de análise de sensibilidade em problemas elásticos [PDF]

open access: yes, 1999
Neste trabalho, desenvolvem-se as expressões continuas de análise de sensibilidade em problemas elásticos lineares. Consideram-se variáveis relacionadas a parâmetros discretos e de forma do problema estrutural. Aspectos da implementação das classes em C +
Bittencourt, Marco Lucio   +1 more
core   +1 more source

Byzantine-Resilient Gradient Coding Through Local Gradient Computations

open access: yesIEEE Transactions on Information Theory
We consider gradient coding in the presence of an adversary controlling so-called malicious workers trying to corrupt the computations. Previous works propose the use of MDS codes to treat the responses from malicious workers as errors and correct them using the error-correction properties of the code.
Christoph Hofmeister   +3 more
openaire   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Diseño óptimo de celosías planas con criterios de estado límite último [PDF]

open access: yes, 1999
En este trabajo se presenta una metodología de cálculo óptimo de estructuras articuladas planas qne permite obtener la forma geométrica y las secciones más convenientes de la estructura.
Andreu, Antoni, Gil, Lluís
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Parâmetros fisiológicos, características de pelame e gradientes térmicos em novilhas nelore no verão e inverno em ambiente tropical

open access: yesBioscience Journal, 2013
Investigou-se a influência da estação do ano sobre as características termorreguladoras e de pelame bem como os gradientes térmicos em novilhas da raça Nelore.
Álvaro Moriya Shiota   +5 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Solución simultánea de las ecuaciones gobernanates del problema termo-elastohidrodinámico de contacto lineal [PDF]

open access: yes, 1998
Un modelo unidimensional del problema termo-elastohidrodinámico de contacto lineal se resuelve numéricamente usando el método de elementos finitos. El sistema de ecuaciones resultante es fuertemente no lineal y se resuelve en forma simultánea mediante ...
Di Paolo, José
core  

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