Results 51 to 60 of about 317,101 (269)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Development and Testing of a Tiered Differential Apparatus for Smart Assessment of Impurity Rate in Mechanically Collected Sugarcane

Agriculture
China is the world’s third-largest sugarcane producer. When mechanically harvested sugarcane enters the sugar mill, impurity rate detection is required.
Sili Zhou, Ye Dai, Shaobo Feng, Pinlan Chen, Bin Yan, Xilin Wang, Zehua Liu, Fengguang He, Shuangmei Qin, Yuping Peng, Jiehao Li   +10 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Estrogen, Progesterone, and Human Epidermal Growth Factor Receptor-2 in Malignant Breast Lesions

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Background and Objective: Breast cancer is the second leading cause of cancer-related deaths in India. Immunohistochemical study helps to carry out a better management of the disease and to determine the prognosis.
Charusheela Rajesh Gore, Sushama Gurwale, Amit Sammi, Indranil Dey, Anjali H Deshpande   +4 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

A METHODOLOGICAL APPROACH TO THE CHARACTERIZATION OF BRAIN GLIOMAS, BY MEANS OF SEMI-AUTOMATIC MORPHOMETRIC ANALYSIS

Image Analysis and Stereology, 2014
The aims of this paper were to present a reliable morphometric procedure for glioma analysis for preliminary prognosis and to develop a semi-automatic procedure that is easy to use.
Artur Dawid Surowka, Dariusz Adamek, Edyta Radwanska, Marek Lankosz, Magdalena Szczerbowska-Boruchowska   +4 more
doaj   +1 more source

Prognostic significance of three‐tiered pathological classification for microvascular invasion in patients with combined hepatocellular‐cholangiocarcinoma following hepatic resection

Cancer Medicine, 2023
Background and Objectives Previous studies have reported that the microvascular invasion three‐tiered grading (MiVI‐TTG) scheme is a better prognostic predictor than the two‐tiered microvascular invasion (MiVI) grading scheme in hepatocellular carcinoma.
Yijun Wu, Hongzhi Liu, Yifan Chen, Jianxing Zeng, Qizhen Huang, Jinyu Zhang, Yongyi Zeng, Jingfeng Liu   +7 more
doaj   +1 more source

Graded Signatures

, 2015
Motivated by the application of anonymous petitions, we formalize a new primitive called "graded signatures", which enables a user to consolidate a set of signatures on a message m originating from l different signers that are members of a PKI. We call the value $$l \in \mathbb {N}$$l∈N, the grade of the consolidated signature.
Aggelos Kiayias, Murat Osmanoglu, Qiang Tang 0005   +2 more
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source