Results 91 to 100 of about 16,696,427 (330)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Gradualism in Free Trade Agreements: A Theoretical Justification [PDF]
A notable feature of many recent trade agreements is the gradual, rather than immediate, reduction of trade barriers. In this paper we model trade liberalization as a cooperative relationship that evolves gradually in a non-cooperative environment.
Richard Chisik
core
La Volte : éditer se conjugue-t-il au singulier ou au pluriel ?
ReS FuturaeBased on a study of the discourses presented on the Editions La Volte website and in interviews with the publisher, the aim is to analyze the construction of the publishing house’s editorial ethos, articulated between a focus on the authors’ collective ...
Oriane Deseilligny
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Kajian Tartibunnuzul Dan Sababunnuzul Dalam Ayat-Ayat Khamr Bagi Pengembangan Metode Dakwah
UlumuddinThe phenomenon of alcohol addiction in Indonesia has rapidly spread across various demographics, from the elderly to the youth. A strategic approach to addressing this issue involves drawing upon the gradual prohibition of alcohol (khamr) established ...
Ahmad Miftahus Sudury +2 more
doaj +1 more source
TOWARDS GRADUAL INTEGRATION OF THE WESTERN BALKANS INTO THE EUROPEAN UNION: THE CASE OF SERBIA
Journal of Liberty and International Affairs, 2022 This paper examined whether the revised enlargement methodology represented another step in the direction of gradual EU membership of the Western Balkans.
Milos Petrovic
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
فصلنامه روانشناسی کاربردی, 2018 Aim: The purpose of this study was to investigate the effectiveness of anger management intervention with cognitive-behavioral approach and gradual muscle relaxation on the quality of marital relationship and moral anxiety among married males of ...
ملکه ناصری فدافن +2 more
doaj
A Case of Protruding Eyeballs and Diminishing Vision
Clinical Medicine Insights: Case Reports, 2009 This case report discusses issues related to a 56-year-old man from Bangalore who presented with complaints of a gradual protrusion of his eyeballs along with diminishing vision for the previous month.
Rakesh Biswas +5 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source