Results 141 to 150 of about 16,696,427 (330)

The metastable birth trajectory [PDF]

The metastable model generalizes the stable population model by allowing net maternity to change exponentially over age and time. As a result, the metastable model generates an exponentially quadratic birth trajectory, which is characterized by a ...
Robert Schoen
core  

Examining the impact of BIM implementation on external environment of AEC industry: A PEST analysis perspective

Developments in the Built Environment
In recent times, there has been a notable increase in the focus on the use of Building Information Modelling (BIM) within the Architecture, Engineering, and Construction (AEC) industry.
Ahsan Waqar, Nasir Shafiq, Idris Othman, Fahad K. Alqahtani, Abdullah Mohammed Alshehri, Mohamed A. Sherif, Hamad R. Almujibah   +6 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Monitoring Procedures for Detecting Gradual Changes

, 2014
This thesis is concerned with the sequential detection of gradual changes in the location of a stochastic process in two different settings: In Chapter 1 we consider a general stochastic process with a linear drift term which exhibits a possible gradual (
Timmermann, Hella
core  

Benzodiazepines: dependence and a therapeutic approach to gradual withdrawal.

Canadian family physician Medecin de famille canadien, 2013
The extensive use of benzodiazepines in the treatment of anxiety and insomnia has led clinicians to wonder about the dependence potential of these drugs. It is estimated that, in Canada, the United States, and western Europe, between 10% and 20% of the population take tranquilizers or hypnotics (mainly benzodiazepines).
D, Blais, L, Petit
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Training in Artificial Intelligence at Veolia: Challenges and Strategy

Field Actions Science Reports
This article analyzes the effects of artificial intelligence (AI) on jobs, skills, and work organization at Veolia, in a context of rapid business transformation.
Anne Du Crest, Mélanie Macé, Morgane Vidal   +2 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Music of Sustained Tones

This thesis accompanies the portfolio of compositions written between 2006 and 2010 and discusses both the overall theoretical concepts, and the specific musical tools, that lie behind their construction.
Glover, Richard
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source