Results 151 to 160 of about 16,696,427 (330)

Multi-Criterion Stability Evaluation and Surface Boundary Method for Slopes

open access: yesAdvances in Civil Engineering
Slope failure generally starts from a single point, where a local failure surface forms, and then progresses to the overall failure. Based on this behavior, this paper proposes a multi-criterion stability evaluation approach for describing progressive ...
Lier Lu   +3 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Space-efficient gradual typing

open access: yes, 2007
Gradual type systems offer a smooth continuum between static and dynamic typing by permitting the free mixture of typed and untyped code. The runtime systems for these languages enforce function types by dynamically generating function proxies.
David Herman   +2 more
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

A unified approach for the detection of gradual transitions in historic material

open access: yes, 2010
Die Diplomarbeit behandelt die automatische Erkennung von Überblendungen (gradual transitions) in historischem Filmmaterial. Wir verwenden Material des russischen Filmemachers Dziga Vertov.
Seidl, Markus Erwin
core  

A Gradual Approach to Technology Based Instruction

open access: yesA Gradual Approach to Technology Based Instruction
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Fuzzy interpolation and level 2 gradual rules

open access: yes, 2003
International audienceFunctional laws may be known only at a finite number of points, and then the function can be completed by interpolation techniques obeying some smoothness conditions. We rather propose here to specify constraints by means of gradual
Prade, Henri   +2 more
core  

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