Results 31 to 40 of about 3,754 (296)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

A PRAGMATIC STUDY OF IRONY IN POLITICAL ELECTORAL SPEECHES

open access: yesآداب الكوفة, 2015
This paper deals with irony in electoral political speeches from pragmatic point of view represented by two American candidates: Barack Obama and George W. Bush.
Fareed Al-Hindawi, Basim Kadhim
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Gradually, then suddenly [PDF]

open access: yesScience, 2020
Racism, climate denial, and coronavirus disease 2019 (COVID-19) are major crises standing in the way of a prosperous future for the United States, and resolution of all three could be enabled by science that is persistently ignored. In Ernest Hemingway's novel The Sun Also Rises , a character named Mike is asked how
openaire   +2 more sources

Gradual session types [PDF]

open access: yesJournal of Functional Programming, 2019
AbstractSession types are a rich type discipline, based on linear types, that lifts the sort of safety claims that come with type systems to communications. However, web-based applications and microservices are often written in a mix of languages, with type disciplines in a spectrum between static and dynamic typing.
ATSUSHI IGARASHI   +4 more
openaire   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Gradual parametricity, revisited [PDF]

open access: yesProceedings of the ACM on Programming Languages, 2019
Bringing the benefits of gradual typing to a language with parametric polymorphism like System F, while preserving relational parametricity, has proven extremely challenging: first attempts were formulated a decade ago, and several designs were recently proposed.
Toro, Matías   +2 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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