Results 51 to 60 of about 3,754 (296)
Gradual extinction reduces reinstatement [PDF]
Frontiers in Behavioral Neuroscience, 2015 The current study investigated whether gradually reducing the frequency of aversive stimuli during extinction can prevent the return of fear. Thirty-one participants of a three-stage procedure (acquisition, extinction and a reinstatement test on day 2) were randomly assigned to a standard extinction (SE) and gradual extinction (GE) procedure.
Shiban, Youssef +3 more
openaire +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Resenha: Gradience, gradualness and grammaticalization: How do they interact?
Revista Linguística, 2015 “Gradience, gradualness and grammaticalization: How do they interact?”, de Traugott e Trousdale (2010), como o título evidencia, trata da interação entre as noções de gradiência, guadualidade e gramaticalização. Com o propósito de responder três questões
José Romerito Silva +1 more
doaj
, 2012 Gradual Ownership Types are a framework allowing programs to be partially annotated with ownership types, while providing the same encapsulation guarantees. The formalism provides a static guarantee of the desired encapsulation property for fully annotated programs, and dynamic guarantees for partially annotated programs via dynamic checks inserted by ...
Sergey, Ilya, Clarke, Dave
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Methodological approach to the noun gender and number categories in textbook for the second grade of elementary school [PDF]
Методичка праксаGiven that the gender and number of nouns are adopted for the first time in the second grade of elementary school in Republic of Serbia. The subject of this research is the way of processing these grammatical categories at the age when the concepts of ...
Vesić Ljubica D., Mitrović Milena B.
doaj +1 more source
Journal of Artificial Intelligence Research, 2005 Argumentation is based on the exchange and valuation of interacting arguments, followed by the selection of the most acceptable of them (for example, in order to take a decision, to make a choice). Starting from the framework proposed by Dung in 1995, our purpose is to introduce 'graduality' in the selection of the best arguments, i.e., to be able to ...
Cayrol, Claudette +1 more
openaire +5 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Language acquisition from the perspective of multi-representational models
Gragoatá, 2006 This paper presents the results of three researches focusing on the acquisition of structured variation of phonological and morphological patterns by children in the speech community of Rio de Janeiro taking the theoretical assumptions of the Usagebased ...
Christina Abreu Gomes +2 more
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