Results 101 to 110 of about 288,081 (257)

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Academic Position in Medical Education Research

Canadian Medical Education Journal, 2010
The Office of Post Graduate Medical Education (PGME), together with the Medical Education and Research Unit (MERU), invites applications for a full-time academic position in medical education research at the Assistant or Associate Professor level.
Tyrone Donnon, PhD
doaj  

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window

Advanced Science, EarlyView.
Direct growth of sp2‐sp3 hybridized BN (HBN) on quartz, enabled by an h‐BN buffer, produces transparent and stable films up to 80 µm thick with high transmittance and strong neutron shielding, making HBN a promising candidate for space windows in long‐term lunar missions.
Dobin Kim, Geunpil Kim, Hwijoon Jeong, Sk Mujaffar Hossain, Satadeep Bhattacharjee, Minjae Isaac Kwon, Yeunjeong Lee, Chanhee Yang, Yeong Seok Ham, Taek‐Soo Kim, Hyowon Moon, Inkyu Park, Seung‐Cheol Lee, Jinhwan Kim, Jongbum Kim, Jaehyun Park   +15 more
wiley   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Asymmetric Active Center Triggers Side‐On Photo‐Fenton‐Like Reaction Through Polar Charge Transfer and Self‐Adapting Sulfur Vacancies

Advanced Science, EarlyView.
The Cu‐Zn3In2S6 photocatalyst (Cu‐ZISV) with asymmetric Cu‐SV‐Zn sites was designed and synthesized to boost peroxymonosulfate (PMS) activation kinetics. The side‐on photo‐Fenton‐like reaction by the asymmetric Cu‐SV‐Zn site accelerated PMS activation and pollutant degradation, and the first‐order kinetic constant of Cu‐ZISV increased by 4.87 times ...
Jiaqi Hu, Xiaoyuan Zhang, Yufei Gao, Jianyi Liu, Xu He, Yu Liu, Jinfeng Lu, Jun Ma   +7 more
wiley   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

An Analysis of Graduate Medical Education Program Coordinator Job Descriptions. [PDF]

J Grad Med Educ
Anderson L, Wright K, Keffler K, Eaton J, Twiss M, Rowland K.   +5 more
europepmc   +1 more source

A Strain Decoupling Packaging Strategy for High‐Fidelity Ultrathin Silicon Shape Sensors for Soft Medical Robotics

Advanced Science, EarlyView.
Reliable soft sensors are essential for precise control in soft medical robots such as endoscopes. We developed ultrathin silicon piezoresistive sensors and their oil‐lubricated slidable packaging, which enables high‐fidelity shape sensing of silicon gauges by mechanically isolating the sensing element within a dual‐layer film.
Hao Liu, Masahito Takakuwa, Michitaka Yamamoto, Yiwen Wang, Tomoyuki Yokota, Takao Someya, Toshihiro Itoh, Seiichi Takamatsu   +7 more
wiley   +1 more source

Financing graduate medical education

Academic Medicine, 1969
openaire   +3 more sources