Results 61 to 70 of about 298,429 (261)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Teaching Critical Thinking in Graduate Medical Education: Lessons Learned in Diagnostic Radiology

Journal of Medical Education and Curricular Development, 2017
The 2014 Institute of Medicine report, Graduate Medical Education that Meets the Nation’s Health Needs , challenged the current graduate medical training process and encouraged new opportunities to redefine the fundamental skills and abilities of the ...
Benjamin Morrissey, Marta E Heilbrun
doaj   +1 more source

Introducing the Journal of Scientific Innovation in Medicine

Journal of Scientific Innovation in Medicine, 2018
Although some may argue that there is no need for yet another journal in science and medicine, the unique Journal of Scientific Innovation in Medicine offers more than a publishing venue in this arena.
I. Michael Leitman
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

O "Currículo Paralelo" dos estudantes de medicina da Universidade Federal de Minas Gerais

Revista Brasileira de Educação Médica
As atividades em busca de complementação da formação e aumento da experiência clínica dos alunos de Medicina - eqüidistantes e livres de controles acadêmicos - configuram o chamado "currículo paralelo".
Ari de Pinho Tavares, Roberto Assis Ferreira, Elisabeth Barboza França, Carlos Alfredo Fonseca Junior, Gustavo Coelho Lopes, Nayanne Gama Teixeira Dantas, Séphora Augusta Vieira Cardoso   +6 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Lived experiences of mentors in an Asian postgraduate program: Key values and sociocultural factors

The Asia Pacific Scholar
Introduction: Mentoring is an essential component of post-graduate medical training programs worldwide, with potential benefits for both mentors and mentees.
Aletheia Chia, Menghao Duan, Sashikumar Ganapathy   +2 more
doaj   +1 more source

A novel approach to the program evaluation committee

BMC Medical Education, 2019
Background The Accreditation Council for Graduate Medical Education requires each residency program to have a Program Evaluation Committee (PEC) but does not specify how the PEC should be designed.
Amy R. Schwartz, Mark D. Siegel, Alfred Ian Lee   +2 more
doaj   +1 more source