Results 221 to 230 of about 644,974 (304)

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

COVID-19 Vaccination Decision-Making for Residents With Dementia in Japanese Long-Term Care Facilities: A National Cross-Sectional Survey. [PDF]

J Gen Fam Med
Oki M, Nagao N, Dozono T, Kamiya K, Miura Y, Takeshita K.   +5 more
europepmc   +1 more source

Institutional audit : Royal Holloway, University of London [PDF]

, 2011

core  

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Delayed endodontic management of traumatically exposed immature maxillary anterior teeth: a case series. [PDF]

Biomater Investig Dent
Ravi V, Singhal R, Sharma M, Namdev R.
europepmc   +1 more source

3D‐Printed Architected Anisotropic Channels for Ultrafast Solar‐Driven Interfacial Evaporation via Localized Thermal Management and Water Layer Structuring

Advanced Science, EarlyView.
A 3D‐printed anisotropic channel evaporator integrates directional geometry with aligned titanium oxide, boron nitride, and chitosan networks to coordinate photon absorption, heat localization, and water transport. Phonon‐guided thermal pathways and interfacial water structuring enable ultrahigh evaporation rates and long‐term salt‐resistant solar ...
Sijia Sun, Dong Jiang, Hengsong Zheng, Shuai Zhang, Ziyuan Cheng, Changtong Mei, Dan Tian, Shilong Yang, Yusuke Yamauchi, Mingzhu Pan   +9 more
wiley   +1 more source

Graduate Training in the Faculty of Nursing at Universidad de Antioquia. A Contribution to Society's Needs for Care. [PDF]

Invest Educ Enferm
Posada Vera EM.
europepmc   +1 more source

Mainstream initial teacher training : operations manual academic year 2012/13 [PDF]

, 2012

core  

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source