Results 121 to 130 of about 179,002 (365)

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies. [PDF]

, 2015
Treatment of hematological malignant disorders has been improved over the last years, but high relapse rate mainly attributable to the presence of minimal residual disease still persists.
Biassoni, Biron, Björklund, Brodin, Bryceson, Burns, Campbell, Cooley, Cooper, Cooper, Curti, Davies, Di Santo, Di Santo, Farag, Fehniger, Fogler, Foley, Freud, Gasser, Gilfillan, Grimm, Guethlein, Herberman, Huntington, Joncker, Kiessling, Killig, King, Kröger, Lajoie, Lanier, Leong, Ljunggren, Lowe, Lundqvist, Mancusi, McQueen, Miller, Moretta, Moretta, Moretta, Nguyen, Oevermann, Ouyang, Perussia, Phillips, Romagnani, Romee, Rosenberg, Rosenberg, Rosenberg, Ruggeri, Santoni, Stabile, Stabile, Stern, Stringaris, Thielens, Torelli, Trinchieri, Trinchieri, Vago, Valés-Gómez, Venstrom, Vivier, Whitelaw, Zorn   +67 more
core   +1 more source

Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts

Advanced Materials Technologies, EarlyView.
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez, Maxime‐Emmanuel Comtois‐Bona, Antony El‐Khoury, Sergio David Garcia Schejtman, Aidan Macadam, Juan‐David Figueroa‐Alegria, Jesus M. Calderon‐Torres, Irene Guzmán‐Soto, Marc Ruel, Erik J. Suuronen, Marcelo Muñoz, Emilio I. Alarcon   +11 more
wiley   +1 more source

Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial

Haematologica, 2015
We conducted a phase III study to test the hypothesis that initial therapy with “lower dose” prednisone is effective and safe for patients with newly diagnosed acute graft-versus-host disease.
Marco Mielcarek, Terrence Furlong, Barry E. Storer, Margaret L. Green, George B. McDonald, Paul A. Carpenter, Mary E.D. Flowers, Rainer Storb, Michael Boeckh, Paul J. Martin   +9 more
doaj   +1 more source

Chronic Graft-versus-host Disease Presenting with Multiple Punctate Intracranial Lesions on Contrast-enhanced Magnetic Resonance Imaging [PDF]

, 2017
Central nervous system graft-versus-host disease can present quite a diagnostic challenge. We herein present a case of histologically-confirmed chronic graft versus host disease (GVHD) involving the central nervous system that occurred at 19 months after
Chiba Shigeru, Nakamagoe Kiyotaka, Nohara Seitaro, Obara Naoshi, Ogawa Shinichi, Sakamoto Noriaki, Sato Taiki, Tamaoka Akira, Terada Makoto, 中馬越 清隆, 千葉 滋, 坂本 規彰, 小原 直, 玉岡 晃   +13 more
core   +1 more source

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

Advanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang, Hui Xue, Xiaohui Zhu, Dong Lin, Zheng Chen, Xin Dong, Junru Chen, Mingchen Shi, Yuchao Ni, Jonathan Cao, Rebecca Wu, Connie Kang, Xinyao Pang, Francesco Crea, Yen‐Yi Lin, Colin C. Collins, Martin E. Gleave, Abhijit Parolia, Arul Chinnaiyan, Christopher J. Ong, Yuzhuo Wang   +20 more
wiley   +1 more source

Computational Approaches for Disease Gene Identification [PDF]

arXiv, 2017
Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of the pleiotropy of genes, the limited number of confirmed disease genes among whole genome and the genetic ...
arxiv  

A randomized phase II trial of tacrolimus, mycophenolate mofetil and sirolimus after non-myeloablative unrelated donor transplantation [PDF]

, 2014
The study is a randomized phase II trial investigating graft-versus-host disease prophylaxis after non-myeloablative (90 mg/m(2) fludarabine and 2 Gy total body irradiation) human leukocyte antigen matched unrelated donor transplantation.
A. A. Langston, A. E. Woolfrey, B. E. Storer, B. Kornblit, B. M. Sandmaier, D. G. Maloney, F. B. Petersen, K. Hubel, L. Vindelov, M. A. Pulsipher, M. B. Maris, M. E. D. Flowers, P. Hari, R. Storb, T. Lange, T. R. Chauncey, W. A. Bethge   +16 more
core   +2 more sources

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

Intentional donor lymphocyte-induced limited acute graft-versus-host disease is essential for long-term survival of relapsed acute myeloid leukemia after allogeneic stem cell transplantation

Haematologica, 2014
The prognosis of patients with relapsed acute myeloid leukemia after allogeneic transplantation is poor. We hypothesized that initial disease control by effective cytoreduction, followed by rapid induction of a profound allo-immune response by donor ...
Matthias Eefting, Peter A von dem Borne, Liesbeth C de Wreede, Constantijn JM Halkes, Sabina Kersting, Erik WA Marijt, Hendrik Veelken, JH Frederik Falkenburg   +7 more
doaj   +1 more source

THE INDUCTION OF GRAFT VERSUS HOST DISEASE IN MICE TREATED WITH CYCLOPHOSPHAMIDE [PDF]

, 1968
Albert H. Owens, George W. Santos
openalex   +1 more source