Results 131 to 140 of about 179,002 (365)

Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]

, 2016
Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Sandra, Koen, t'Kindt, Ruben, Van Aelst, Britt, Vandekerckhove, Philippe, Zachée, Pierre   +7 more
core   +2 more sources

Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study

Advanced Science, EarlyView.
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu, Zhuo‐Yu An, Li‐Juan Cui, Meng‐Yu Xiao, Ye‐Jun Wu, Wei Li, Bang‐Shuo Zhang, Li Yu, Jia Feng, Zhuo‐Gang Liu, Ru Feng, Zhong‐Xing Jiang, Rui‐Bin Huang, Hong‐Mei Jing, Jin‐Hai Ren, Xiao‐Yu Zhu, Yun‐Feng Cheng, Yu‐Hua Li, He‐Bing Zhou, Da Gao, Yi Liu, Fan Yu, Xin Wang, Jian‐Lin Qiao, Dai‐Hong Hu, Lu‐Lu Wang, Meng‐Tong Zang, Qi Chen, Qing‐Yuan Qu, Jian‐Ying Zhou, Meng‐Lin Li, Yu‐Xiu Chen, Qiu‐Sha Huang, Hai‐Xia Fu, Yue‐Ying Li, Qian‐Fei Wang, Xiao‐Jun Huang, Xiao‐hui Zhang, the Cooperative ITP Working Group   +38 more
wiley   +1 more source

Graft-versus-Leukemia Effect of Nonmyeloablative Stem Cell Transplantation [PDF]

, 2009
Nonmyeloablative stem cell transplantation (NST) is increasingly used with beneficial effects because it can be applied to older patients with hematological malignancies and those with various complications who are not suitable for conventional ...
Alyea, Alyea, Alyea, Ambrosini, Anderson, Andreani, Antin, Antin, Attal, Attal, Azuma, Bardos, Baron, Baron, Baron, Baron, Baron, Bethge, Bjorkstrand, Blazar, Blazar, Blazar, Blazar, Bornhauser, Bornhauser, Cavo, Chakraverty, Chan, Chen, Childs, Childs, Cho, Choi, Collins, Corradini, Crawley, Cudkowicz, Cutler, Dazzi, Dickinson, Dreger, Duffner, Estey, Feinstein, Fukuda, Gaiger, Gao, Garban, Giralt, Giralt, Goulmy, Gribben, Hamaki, Hegenbart, Hori, Igarashi, Imamura, Imamura, Jones, Junji Tanaka, Kawase, Kawase, Khouri, Khouri, Khouri, Kolb, Kolb, Kottaridis, Kruger, Kwak, Lee, Liang, Lokhorst, Lokhorst, Mackinnon, Maloney, Mandigers, Marijit, Maris, Marks, Martinelli, Martino, Maruyama, Masahiro Imamura, Matte, McSweeney, Michallet, Miller, Miura, Molldrem, Molldrem, Murai, Murphy, Nagler, New, Ohata, Oka, Or, Ota, Paczesny, Porter, Porter, Porter, Rajkumar, Rao, Ratanatharthorn, Reddy, Reddy, Reker, Richardson, Robinson, Rondon, Rosinski, Ruggeri, Ruggeri, Saito, Salama, Sasaki, Schwartz, Scott, Serody, Shigematsu, Shlomchik, Slavin, Spierings, Spitzer, Storb, Sullivan, Sun, Tanaka, Tanaka, Taylor, Terwey, Tricot, Ueno, Valcarcel, Warren, Wysocki, Wysocki, Yong, Yong, Yotnda, Zorn   +142 more
core   +2 more sources

Meta-analysis of Gene Expression in Neurodegenerative Diseases Reveals Patterns in GABA Synthesis and Heat Stress Pathways [PDF]

arXiv, 2019
Neurodegenerative diseases are characterized as the progressive loss of neural cells, e.g. neurons, glial cells. Ageing, monogenic variations, viral infections, and many other factors are determined and speculated as causes for them. While many individual genes, such as APP for Alzheimer disease and HTT for Huntington disease, and biological pathways ...
arxiv  

Aging‐induced Alternation in the Gut Microbiota Impairs Host Antibacterial Defense

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Bacterial infections in older individuals often result in worse outcomes, but the mechanisms remain unclear. This study reveals that aging‐induced alterations in gut microbiota impair host antibacterial defense mechanisms, and exacerbate the consequences of bacterial infections.
Peng Gu, Rongjuan Wei, Ruofan Liu, Qin Yang, Yuxuan He, Jianbin Guan, Wenhao He, Jiaxin Li, Yunfei Zhao, Li Xie, Jie He, Qingling Guo, Jiajia Hu, Jingna Bao, Wandang Wang, Jiayin Guo, Zhenhua Zeng, Zhongqing Chen, Yong Jiang, Zhanguo Liu, Peng Chen   +20 more
wiley   +1 more source

Enfermedad injerto contra huesped: sus manifestaciones bucales

Revista Cubana de Estomatología
La enfermedad injerto contra huésped es la principal complicación que sufren los pacientes que han recibido trasplante alogénico. Se produce como consecuencia de una reacción inflamatoria exagerada mediada por los linfocitos del donante y estimulada por ...
Claudia Marcela Hernández Cancino, Renata Córdova Petersen, Isabel Nemoto Vergara Sasada, Caroline Siviero Dillenburg, Ingeburg Hellwig   +4 more
doaj  

Establishment of early donor engraftment after reduced-intensity allogeneic hematopoietic stem cell transplantation to potentiate the graft-versus-lymphoma effect against refractory lymphomas [PDF]

, 2003
Reduced-intensity allogeneic hematopoietic stem cell transplantation (alloHSCT), which typically results in mixed chimerism initially after transplantation, has had limited efficacy in chemotherapy-refractory lymphomas.
Bishop, Michael R., Castro, Kathleen, Fowler, Daniel H., Gea-Banacloche, Juan, Gress, Ronald, Hou, Jeannie Whit-Shan, Kasten-Sportes, Claude, Marchigiani, Donna, Odom, Jeanne, Steinberg, Seth M., Wilson, Wyndham H.   +10 more
core   +1 more source

Snap and Diagnose: An Advanced Multimodal Retrieval System for Identifying Plant Diseases in the Wild [PDF]

arXiv
Plant disease recognition is a critical task that ensures crop health and mitigates the damage caused by diseases. A handy tool that enables farmers to receive a diagnosis based on query pictures or the text description of suspicious plants is in high demand for initiating treatment before potential diseases spread further.
arxiv  

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation

Haematologica, 2012
Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion of T cells with suppressive properties.
Teresa Caballero-Velázquez, Luis Ignacio Sánchez-Abarca, Silvia Gutierrez-Cosio, Belén Blanco, Cristina Calderon, Carmen Herrero, Soraya Carrancio, Concepción Serrano, Consuelo del Cañizo, Jesús F. San Miguel, José A. Pérez-Simón   +10 more
doaj   +1 more source