Results 181 to 190 of about 179,002 (365)

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

open access: yesAdvanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz   +24 more
wiley   +1 more source

A nationwide assessment of hepatocellular adenoma resection: Indications and pathological discordance

open access: yesHepatology Communications, EarlyView., 2022
Abstract Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.
Martijn P. D. Haring   +70 more
wiley   +1 more source

A severity‐based tumor‐superior mesenteric/portal vein interface grading criteria as a predictor of survival outcomes in pancreatic head ductal adenocarcinoma patients undergoing pancreaticoduodenectomy following neoadjuvant chemoradiotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
PDAC patients with the radiological severe interface (≥25 contact length and ≥210 degrees circumferential tumor‐SMV/PV interface) may help predict poor survival outcomes preoperatively. Abstract Aim To assess the ability of a new severity‐based tumor‐superior mesenteric/portal vein interface criteria to predict survival outcomes in pancreatic ductal ...
Benson Kaluba   +9 more
wiley   +1 more source

Azithromycin for Prevention of Graft-Versus-Host Disease: A Randomized Placebo-Controlled Trial

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2018
Background: Allogeneic hematopoietic stem cell transplantation has been used widely to treat various types of malignant and non-malignant disorders. Graft-versus-host disease is one of the main complications of this procedure which is associated with ...
Maryam Barkhordar   +4 more
doaj  

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

open access: yesAggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail   +5 more
wiley   +1 more source

GRAFT-VERSUS-HOST DISEASE PRODUCED WITH WHOLE BLOOD

open access: bronze, 1969
Seymour Levine, Masao Iwahara
openalex   +1 more source

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