Results 11 to 20 of about 117,056 (302)
Review of Cutaneous Graft-vs-Host Disease
Actas Dermo-Sifiliográficas (English Edition), 2016 Graft-vs-host disease (GVHD) is a multisystem disease that arises as a complication of allogeneic hematopoietic stem cell transplant. It is due to recognition of the recipient's tissues by immune cells from the donor. The skin and mucous membranes are the organs most commonly affected.
Ballester-Sánchez R +3 more
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JAMA Network Open, 2021 Key Points Question Is ruxolitinib an option for patients with steroid-refractory chronic graft-vs-host disease, and what characteristics are associated with treatment response?
Hengwei Wu +10 more
semanticscholar +1 more source
Dermatology Online Journal, 2013 We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented ...
Tran, Kathleen +3 more
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Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD
Biology, 2023 Graft-versus-host disease (GVHD) is a life-threatening systemic complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by dysregulation of T and B cell activation and function, scleroderma-like features, and multi-organ ...
Deepika Raman +7 more
doaj +1 more source
Journal of Clinical Investigation, 2021 Inhibitors of calcineurin phosphatase activity (CNIs) such as cyclosporin A (CsA) are widely used to treat tissue transplant rejection and acute graft-versus-host disease (aGVHD), for which inhibition of NFAT-dependent gene expression is the mechanistic ...
S. Otsuka +5 more
semanticscholar +1 more source
Role of HRCT Chest in Post Stem Cell Transplant Recipients Suspected of Pulmonary Complications [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Stem cell transplantation is today’s procedure of choice for management of various hematopoietic malignant and severe immunogenic disorders. High Resolution Computed Tomography (HRCT) is a common technique for the diagnosis of pulmonary
Abhishek Dwivedi +3 more
doaj +1 more source
Biomarkers of graft-vs-host disease: Understanding and applications for the future
World journal of transplantation, 2021 Hematopoietic stem cell transplantation (HSCT) is widely performed as a treatment for malignant blood disorders, such as leukemia. To achieve good clinical outcomes in HSCT, it is necessary to minimize the unfavorable effects of acute graft-vs-host ...
M. Nagasawa
semanticscholar +1 more source
Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review [PDF]
Annals of Coloproctology, 2020 Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition.
Kwang-Seop Song +9 more
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Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series [PDF]
Annals of Rehabilitation Medicine, 2019 Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation on joint contractures in children
Minji Jung, In Young Sung, Eun Jae Ko
doaj +1 more source
Prevention of graft-vs.-host disease [PDF]
Expert Opinion on Pharmacotherapy, 2012 Allogeneic hematopoietic cell transplantation (HCT) is a curative treatment for many malignant and non-malignant hematologic disorders. However, graft-vs.-host disease (GVHD) remains a major complication of allogeneic HCT and limits the success of this approach.This paper reviews recent developments in the prevention of acute and chronic GVHD.
Andrew R, Rezvani, Rainer F, Storb
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