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Ocular Manifestations of Graft-vs-Host Disease

Ophthalmology, 1983
In patients who have graft-vs-host disease (GVHD) after bone marrow transplantation, ocular involvement occurs in approximately 60% of cases. Among 13 such GVHD patients, the most frequent ocular manifestations included keratoconjunctivitis sicca, cicatricial lagophthalmos, and sterile conjunctivitis and uveitis.
R M, Franklin   +5 more
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Life-threatening graft-vs-host disease

Clinics in Dermatology, 2005
Hematopoietic stem cell transplant (SCT) is considered standard therapy for a variety of malignant and nonmalignant diseases. Graft-versus-host disease (GVHD) still represents today a major complication of hematopoietic SCT. Two types of GVHD have traditionally been recognized on the basis of the time of onset following transplantation, distinct ...
Erich, Vargas-Díez   +3 more
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Graft vs. Host Disease

2004
Transplantation immunobiology: thymic T-cell development MHC class 1: structure and function MHC class II: structure and function biological inhibitors of lymphocyte coreceptors for antigen-specific immunosuppression immunosuppression andimmunophilin ligands: cyclosporin A, FK506, and rapamycin leucocyte adhesion, trafficking, and migration cytokine ...
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Blood Transfusions and Graft-vs-Host Disease

Archives of Dermatology, 1990
Decoste et al 1 report on transfusion-associated graft-vs-host disease (GVHD) in this issue of theArchivesand raise important considerations for dermatologists evaluating morbilliform erythemas and exanthems. In healthy individuals, such eruptions are frequently attributed (correctly or otherwise) to a drug sensitivity or reaction, often on criteria of
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[Graft vs host disease].

Pathologie-biologie, 2006
Graft vs host disease is a serious immunological complication of allogeneic haematopoietic cell transplantation, leading to a significant morbidity and mortality. It occurs when donor T lymphocyte react to foreign host cells. The physiopathology is a more complex process implicating host tissues damage caused by the conditioning regimen, cytokines ...
V, Moalic, C, Ferec
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Antigen presentation in graft-vs-host disease

Experimental Hematology, 2003
Graft-vs-host disease (GVHD) and the sequela of immunosuppression used to prevent it remain major causes of morbidity and mortality in allogeneic stem cell transplantation (alloSCT). In particular, GVHD and ineffective T-cell immune reconstitution significantly decreases the enthusiasm for offering alloSCT to patients with non-malignant inherited ...
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Acute Graft-vs-Host Disease

Archives of Dermatology, 1987
• Graft-vs-host disease (GVHD) is a frequent complication of allogeneic bone marrow transplantation but has been infrequently reported following autologous or syngeneic bone marrow transplantation. Ninety-six autologous and 19 syngeneic marrow transplants were performed at our institution between July 1977 and March 1984. We report acute cutaneous GVHD
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Photopheresis in graft‐vs.‐host disease

ISBT Science Series, 2007
Keywords: Extracorporeal photopheresis (ECP); Graft versus host disease (GvHD); Haematopoietic stem cell transplantation (HSCT)
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Acute Graft-vs-Host Disease

2004
Hemopoietic stem cell transplantation (HSCT) involves the transfer of cells that produce hemopoietic and lymphoid progeny. For donor cells to accept the host environment as “self ” requires that newly developing alloreactive T lymphocytes and mature donor T lymphocytes contained in the transplant inoculum be eliminated or inactivated, and only cells ...
Uwe Platzbecker, H. Joachim Deeg
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Cyclosporin A and Graft-vs.-Host Disease

The American Journal of Dermatopathology, 1986
J, Palou   +5 more
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