Results 251 to 260 of about 86,953 (307)
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2000
The transplantation of healthy hematopoietic stem cells into a patient with aplastic anemia or leukemia is potentially curative therapy, but the development of acute graftvs-host disease (GVHD), which often occurs even when the donor and recipient are siblings fully matched at the human leukocyte antigen (HLA) loci, significantly limits survival.The ...
Thomas R. Spitzer, Robert Sackstein
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The transplantation of healthy hematopoietic stem cells into a patient with aplastic anemia or leukemia is potentially curative therapy, but the development of acute graftvs-host disease (GVHD), which often occurs even when the donor and recipient are siblings fully matched at the human leukocyte antigen (HLA) loci, significantly limits survival.The ...
Thomas R. Spitzer, Robert Sackstein
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Bone Marrow Transplantation, 2005
JLM Ferrara, KR Cooke and HJ Deeg (eds) Third edition, 2005. Marcel Dekker, New York, NY, USA, ISBN: 0-8247-5472-7, 645pp.
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JLM Ferrara, KR Cooke and HJ Deeg (eds) Third edition, 2005. Marcel Dekker, New York, NY, USA, ISBN: 0-8247-5472-7, 645pp.
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Approaches to graft‐vs‐host disease
Pediatric Transplantation, 2005Abstract: Graft‐vs‐host disease (GVHD) is one of the most difficult problems in stem cell transplantation. It is best considered in the context of the normal immune response. The role of the immune system is to identify and eliminate foreign antigens.
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Pathologie-biologie, 2006
Graft vs host disease is a serious immunological complication of allogeneic haematopoietic cell transplantation, leading to a significant morbidity and mortality. It occurs when donor T lymphocyte react to foreign host cells. The physiopathology is a more complex process implicating host tissues damage caused by the conditioning regimen, cytokines ...
V, Moalic, C, Ferec
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Graft vs host disease is a serious immunological complication of allogeneic haematopoietic cell transplantation, leading to a significant morbidity and mortality. It occurs when donor T lymphocyte react to foreign host cells. The physiopathology is a more complex process implicating host tissues damage caused by the conditioning regimen, cytokines ...
V, Moalic, C, Ferec
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Biology of Graft-vs.-Host Disease
Journal of Pediatric Hematology/Oncology, 1993Graft-vs.-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation, which is an important approach for the treatment of various diseases. In experimental animal models, lethal GVHD can be induced in major histocompatibility complex (MHC)-matched strain combinations that differ in their expression of multiple minor ...
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Skin Changes in Graft-vs-Host Disease
Southern Medical Journal, 1976In this review of the clinical and histopathologic manifestations of the graft-vs-host reaction, the characteristic changes in the skin are given particular emphasis, since they are among the earliest and most obvious signs of this syndrome. The acute and chronic forms of graft-vs-host disease are distinguished, with notation of their different ...
R L, Spielvogel, S, Ullman, R W, Goltz
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Graft–Vs.–Host Disease After Liver Transplantation
Hepatology, 1990Clinically evident, generalized graft–vs.–host disease is not thought to occur as a consequence of transplantation of most solid organs. The large inoculum of donor lymphoid cells required and the inability of the recipient to destroy these passenger cells are apparently rarely produced by solid–organ transplantation. However,
G, Alexander, B, Portmann
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2004
Transplantation immunobiology: thymic T-cell development MHC class 1: structure and function MHC class II: structure and function biological inhibitors of lymphocyte coreceptors for antigen-specific immunosuppression immunosuppression andimmunophilin ligands: cyclosporin A, FK506, and rapamycin leucocyte adhesion, trafficking, and migration cytokine ...
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Transplantation immunobiology: thymic T-cell development MHC class 1: structure and function MHC class II: structure and function biological inhibitors of lymphocyte coreceptors for antigen-specific immunosuppression immunosuppression andimmunophilin ligands: cyclosporin A, FK506, and rapamycin leucocyte adhesion, trafficking, and migration cytokine ...
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CNS angiitis in graft vs host disease
Neurology, 2002Graft-vs-host disease (GVHD) is a potentially treatable cause of progressive neurologic decline after bone marrow transplantation (BMT). The authors present histologic confirmation of CNS granulomatous angiitis in a child with chronic GVHD after BMT. Since cranial MRI showed only nonspecific findings, CNS vasculitis associated with GVHD after BMT may ...
M, Ma +5 more
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Archives of Dermatology, 1987
• Graft-vs-host disease (GVHD) is a frequent complication of allogeneic bone marrow transplantation but has been infrequently reported following autologous or syngeneic bone marrow transplantation. Ninety-six autologous and 19 syngeneic marrow transplants were performed at our institution between July 1977 and March 1984. We report acute cutaneous GVHD
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• Graft-vs-host disease (GVHD) is a frequent complication of allogeneic bone marrow transplantation but has been infrequently reported following autologous or syngeneic bone marrow transplantation. Ninety-six autologous and 19 syngeneic marrow transplants were performed at our institution between July 1977 and March 1984. We report acute cutaneous GVHD
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