Results 81 to 90 of about 1,940,591 (256)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Sinus graft infection management: systematic review

, 2021
The aim of this study was to systematically review sinus graft infection management in order to define which protocols should be implemented. The terms searched in each database were “sinus graft infection management”, “maxillary sinus lift infection”, “
Schlund, Matthias
core   +1 more source

Case report: Vascular graft infection due to Aspergillus species presenting with recurrent vascular occlusion

BMC Cardiovascular Disorders, 2022
Background An aortic graft implantation is an effective therapeutic method for various aortic diseases. However, it is known that sometimes these implanted grafts can be the foci of infections. Here we report a rare case of graft infection that presented
Ayami Tano, Koichi Kato, Yoshimasa Seike, Hitoshi Matsuda, Takashi Suzue, Yoshihiro Kaneko, Misato Kodama, Yuichi Sawayama, Akashi Miyamoto, Noriaki Yagi, Yoshihisa Nakagawa   +10 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Optimizing treatment of proximal thoracic aortic graft infectionsCentral MessagePerspective

JTCVS Open
Objectives: To describe treatment, assess outcomes, and identify risk factors for primary infection, reinfection, and death in patients with proximal thoracic aortic graft infection.
Matthew A. Thompson, MD, Toshiki Fujiyoshi, MD, PhD, Benjamin Kramer, DO, PhD, Ashley M. Lowry, MS, MEd, Haytham Elgharably, MD, Steven Gordon, MD, Vidyasagar Kalahasti, MD, Nabin Shrestha, MD, Patrick Vargo, MD, Eugene H. Blackstone, MD, Eric E. Roselli, MD   +10 more
doaj   +1 more source

HIV seroprevalence and its effect on outcome of moderate to severe burn injuries: A Ugandan experience. [PDF]

, 2011
\ud \ud HIV infection in a patient with burn injuries complicates the care of both the patient and the treating burn team. This study was conducted to establish the prevalence of HIV among burn patients in our setting and to compare the outcome of these ...
Kakande, Ignatius, Ssentongo, Robert, Ignatius Kakande, Chalya, Phillipo L, Robert Ssentongo, Phillipo L Chalya   +5 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Double-Layered Circular Advancement Flap for Reconstruction of Inguinal Defects

Turkish Journal of Plastic Surgery, 2017
Objective: Vascular graft infections are rare complications but can lead to life-threatening outcomes for the patient. Conventional treatment methods are the removal of the vascular graft and an extra-anatomic by-pass procedure.
Enver Arpaci, Serdar Altun
doaj   +1 more source

Cadaveric aorta implantation for aortic graft infection [PDF]

, 2016
This case report describes a 73-year-old gentleman who underwent explantation of an infected prosthetic aorto-iliac graft and replacement with a cryopreserved thoracic and aorto-iliac allograft.
Ali, Asad, Bahia, Sandeep S.S., Ali, Tahir   +2 more
core   +1 more source