Results 131 to 140 of about 508,484 (293)
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab +8 more
wiley +1 more source
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole +12 more
wiley +1 more source
Hierarchical Membrane for Photoelectrostatically Gated Monovalent‐Divalent Ion Separation
We report a hierarchical poly(ionic liquid)–carbon nitride membrane supported on anodic alumina for efficient monovalent/divalent ion separation. Confined nanochannels and tailored interfacial ion interactions enable exceptional K+/Mg2+ ( > 500) and Li+/Mg2+ ( > 200) selectivities, offering a promising strategy for advanced aqueous ion separations ...
Enis Oğuzhan Eren +3 more
wiley +1 more source
Graft rejection after hematopoietic cell transplantation with nonmyeloablative conditioning
Graft rejection after hematopoietic cell transplantation (HCT) with nonmyeloablative conditioning is a rare but serious clinical problem. Graft rejection and salvage therapy in eight patients in a retrospective analysis of 124 consecutive patients is ...
Vindelov, L.L. +8 more
core +1 more source
Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang +8 more
core
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long +3 more
wiley +1 more source
The susceptibility of baboons to the novel immunosuppressant, FTY720 [PDF]
Bibliography: leaves 109-118.Since there is a major scarcity of donor organs world-wide, the experimental search for human organs has focused on two alternatives; mechanical devices and cross-species transplants.
Semple, P L
core
Body donor programs in Australia and New Zealand: Current status and future opportunities
Abstract Body donation is critical to anatomy study in Australia and New Zealand. Annually, more than 10,000 students, anatomists, researchers, and clinicians access tissue donated by local consented donors through university‐based body donation programs. However, little research has been published about their operations.
Rebekah A. Jenkin, Kevin A. Keay
wiley +1 more source
Abstract In patients with recurrent anterior shoulder dislocation and glenoid bone loss between 10% and 20%, isolated Bankart repair remains associated with a certain rate of postoperative redislocation. The optimal management for this patient subset is controversial. We describe an all‐arthroscopic technique using allogeneic bone strips for free graft
Yingbin Wu +5 more
wiley +1 more source

