Results 131 to 140 of about 537,363 (298)

AI‐Based Immortality: The Ethical Advantage of the Aretai Approach

AI &Innovation, EarlyView.
ABSTRACT The convergence of artificial intelligence, digital identity technologies, and biogerontological ambitions has produced a novel set of philosophical problems that have not yet been adequately addressed within mainstream bioethical discourse. Digital life extension—encompassing AI‐generated avatars, neural data preservation, mind uploading, and
Mirko Daniel Garasic
wiley   +1 more source

Clinical and biochemical characteristics in 90 episodes of acute graft pyelonephritis (AGPN) and acute graft rejection.

, 2015
Values are expresses as mean ± SD or median (range) or number (percentage). BUN, blood urea nitrogen; Cr, creatinine; CRP, C-reactive protein; DNI, delta neutrophil index; Hb, hemoglobin; KT, kidney transplant; PCT, procalcitonin; WBC, white blood cell ...
Eun Jung Kim (783746), Ji-Young Park (194338), Jieun Oh (783748), Soo Jin Kim (783747), Dong Ho Shin (299513)   +4 more
core   +1 more source

‘Shelter is a Dignity’: Rental Racism, Stress and Housing (In)justice

Australian Journal of Social Issues, EarlyView.
ABSTRACT Australia's private rental sector is in crisis, and culturally and racially minoritised renters face compounded harms through both covert and everyday direct forms of rental racism. Drawing on five community‐based focus groups in Melbourne (n = 37), the paper explores how racism manifests across the rental pathway and how it structures the ...
Erika Martino, Ilan Wiesel, Ang Li, Rebecca Bentley   +3 more
wiley   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

Advanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

New Paradigms in Rejection Monitoring: Lymphocyte Subsets as Noninvasive Graft Markers in Vascularized Composite Allotransplantation

Plastic and Reconstructive Surgery, Global Open
Background:. In vascularized composite allotransplantation, face transplantation stands as a transformative intervention for patients with severe facial disfigurement. Monitoring of graft rejection, however, remains a critical challenge. This study aimed
Sachin R. Chinta, BS, Alay R. Shah, MD, David L. Tran, MD, Wen-Yu Lee, MS, Massimo Mangiola, PhD, Bruce E. Gelb, MD, Daniel J. Ceradini, MD, Eduardo D. Rodriguez, MD, DDS   +7 more
doaj   +1 more source

Kaplan-Meier curves for rejection/graft loss according to TAC or CsA.

Kaplan-Meier curves for rejection/graft loss according to TAC or CsA.
Eliana Ferroni (13798504), Gaia Bedeschi (13798495), Marco Finocchietti (12283607), Alessandro Cesare Rosa (11482697), Stefania Spila Alegiani (12422174), Lucia Masiero (3475271), Olivia Leoni (7432340), Arianna Bellini (16789884), Maurizio Nordio (13798501), Stefano Ledda (13798516), Marina Davoli (403904), Valeria Belleudi (2851919), Antonio Addis (29436), Marco Massari (42328), Ersilia Lucenteforte (4510057), Massimo Cardillo (9709207), Silvia Pierobon (13798498), Giuseppe Piccolo (13798510), Donatella Garau (10184969)   +18 more
core   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Does lymphocyte cross-matching predict acute rejection and graft survival in liver transplantation

, 2012
Does lymphocyte cross-matching predict acute rejection and graft survival in liver ...
최기홍, 김명수, 김순일, 주만기, 최진섭, 허규하, 주동진   +6 more
core  

Type I Interferon Drives Dysfunction of a Distinct CD8+ HLA‐DRB1+ T Cell Subset in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long, Elio Carmona, Mikhail G. Dozmorov, Amr H. Sawalha   +3 more
wiley   +1 more source