Results 111 to 120 of about 537,363 (298)

Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients

Scientific Reports, 2017
Pneumocystis jirovecii pneumonia (PJP) is a potentially life-threatening infection that occurs in immunocompromised patients. The aim of this study was to evaluate risk factors for PJP in kidney transplantation recipients.
Su Hwan Lee, Kyu Ha Huh, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Juhan Lee, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Yu Seun Kim, Song Yee Kim   +11 more
doaj   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

Advanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy, Abdalmonam Jadou Nejma, Mohammad Tarique, Amod Talekar, Shengli Wu, Brianna Ha, Yifei Jiang, Esma S. Yolcu, Lonnie D. Shea   +8 more
wiley   +1 more source

Transforming Gas Separations with Scalable Carbon Molecular Sieve Membranes Enabled by Chemically Tuned Hollow‐Fiber Precursors

Advanced Science, EarlyView.
We established a broadly tunable network‐polymer platform for polyimide‐based precursor membranes, extendable to various diamines. Ultrahigh selectivity with demonstrated aging resistance, and scalability via hollow fiber CMS engineering collectively establishes broad and lasting impact for the membrane science and engineering communities.
Yuhe Cao, Zhongyun Liu, Zahra Shomali, Jinyoung Kim, Steven Schlosser, Ryan P. Lively, William J. Koros   +6 more
wiley   +1 more source

Evolution of Rejection Rates and Kidney Graft Survival: A Historical Analysis

, 2009
New immunosuppressive regimens have dramatically reduced rejection rates but this positive effect has not been followed by an improvement in long-term graft outcomes.
Ortuño, J, A. Fernández-Rodriguez, Rodríguez-Mendiola, N, Teruel, J L, F.J. Burgos, Galeano, C, J.J. Villafruela, J.L. Teruel, Ponte, Belen, B. Ponte, J. Ortuño, C. Galeano, N. Rodríguez-Mendiola, R. Marcén, Burgos, F J, Marcén, R, Fernández-Rodriguez, A, Villafruela, J J   +17 more
core   +1 more source

Toward Rational Design of Aqueous Battery Membranes Beyond the Selectivity‐Conductivity Trade‐Off

Advanced Science, EarlyView.
This review examines sulfonated membranes for redox flow batteries. It focuses on proton transport mechanism, membrane design, performance limits, optimization strategies, and the pathway from molecular design to membrane manufacturing. ABSTRACT Electrochemical energy‐storage systems increasingly require membranes that can simultaneously deliver fast ...
Jinkang Liu, Mingbo Xie, Zhenghao Wang, Huacun Li, Jun Xie, Pan Liu, Qingwei Wang, Xu Yan, Meiqing Shi, Liyuan Chai, Yue Luo, Zining Tang, Rui Tan, Liyuan Zhang   +13 more
wiley   +1 more source

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

Advanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng, Qinlian Jiao, Jiankang Zhu, Yidan Ren, Xiaoyu Teng, Xin Su, Zigan Li, Yuxuan Cai, Xiaoyan Liu, Yunshan Wang, Guangyong Zhang   +10 more
wiley   +1 more source

A 13-year descriptive study of corneal transplants at a tertiary, teaching hospital in northwest Iran [PDF]

Health Science Monitor
Background & Aims: Corneal transplantation is considered the most transplanted solid tissue in humans. The purpose of the present investigation was to recognize the main indications and risk factors for allograft rejection.
Naser Samadi Aidenloo, Qader Motarjemizadeh, Ayyub Shamsi   +2 more
doaj  

Prevalence of acute graft pyelonephritis (AGPN) and acute rejection according to a DNI cutoff of 2.7%.

, 2015
DNI, delta neutrophil indexPrevalence of acute graft pyelonephritis (AGPN) and acute rejection according to a DNI cutoff of 2.7%.
Eun Jung Kim (783746), Ji-Young Park (194338), Jieun Oh (783748), Soo Jin Kim (783747), Dong Ho Shin (299513)   +4 more
core   +1 more source

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

Advanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang, Wenwei Liu, Hufei Wang, Yuxin Wu, Yuanchen Ma, Xiaofeng Wang, Tianxiang Lei, Qiao Tang, Yebohao Zhou, Weiqiang Li, Andy Peng Xiang, Wu Song   +11 more
wiley   +1 more source