Results 101 to 110 of about 537,363 (298)
Advanced Science, EarlyView.Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami +7 more
wiley +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
BJS (British Journal of Surgery), EarlyView., 2020 This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
, 2011 Metabolomic identification of potential biomarkers for acute graft rejection of renal transplantation by using RPLC and HILIC coupled with mass ...
石先哲 +3 more
core +1 more source
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Advanced Science, EarlyView.Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source
Biomarkers for corneal graft rejection?
, 2009 Despite the many developments in immunosuppressive therapy, corneal graft rejection still is the leading cause for graft failure.1 This clinical scenario is a constant headache for ophthalmologists that regularly perform corneal transplants.
P Hossain, Hossain, P.
core +1 more source
DSA are associated with more graft injury, more fibrosis and upregulation of rejection associated transcripts in subclinical rejection. [PDF]
, 2019 Background: Subclinical T cell-mediated rejection (subTCMR) is commonly found after liver transplantation and has a good short-term prognosis, even when it is left untreated.
Höfer, Anne +8 more
core +1 more source
Wearable E‐Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems
Advanced Science, EarlyView.The graphical abstract highlights the role of conductive materials and textile fabrication techniques in enabling smart textiles for cardiovascular applications. It showcases textile‐based ECG monitoring, pulse sensing, hemodynamic monitoring, and cardiovascular tissue engineering, while emphasizing the challenges and design considerations that govern ...
Bangul Khan +3 more
wiley +1 more source
Research in Cardiovascular MedicineIntroduction: Cytomegalovirus (CMV) infection is mainly associated with acute or chronic graft rejection in various solid organs. This study was conducted with the aim of evaluating the plasma viral load of CMV infection in postheart transplant patients ...
Kambiz Mozaffari +6 more
doaj +1 more source
TBHsp70 delays skin graft rejection.
, 2013 (A) Skin grafts were immersed in a PBS solution (500 µl) containing TBHsp70 (30 µg) or PBS alone for 60 minutes at 4°C. After this, the skin graft was sutured to the exposed tissue of the recipient.
Ana Paula Ornaghi (359015) +10 more
core +1 more source
Advanced Science, EarlyView.Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana +19 more
wiley +1 more source