Results 81 to 90 of about 508,484 (293)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Corneal allograft rejection: Risk factors, diagnosis, prevention, and treatment

Indian Journal of Ophthalmology, 1999
Recent advances in corneal graft technology, including donor tissue retrieval, storage and surgical techniques, have greatly improved the clinical outcome of corneal grafts.
Dua Harminder, Azuara-Blanco Augusto
doaj  

Immune checkpoint inhibitors use in liver transplantation for hepatocellular carcinoma: a global cohort study

BMC Medicine
Background Hepatocellular carcinoma (HCC) remains a major contributor to global cancer mortality, with liver transplantation (LT) offering curative potential for patients in the early stages.
Delin Ma, Pengcheng Wei, Qian Cheng, Jialing Hao, Zuyin Li, Zhuomiaoyu Chen, Wenzai Shi, Zhigao Yuan, Chen Lo, Yongjing Luo, Liyi Qiao, Jie Gao, Jiye Zhu, Zhao Li   +13 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Transplantation of Long-term Cultured Porcine Islets in the Rat: Prolonged Graft Survival and Recipient Growth on Reduced Immunosuppression

Cell Transplantation, 2010
To evaluate whether further improvement in porcine islet xenotransplantation is feasible, a number of questions were addressed. Earlier we showed significant improvement in the nude mouse of the porcine islets by selection through long-term culture.
Josephine K. R. A. Rijkelijkhuizen, Annemiek Töns, Onno T. Terpstra, Eelco Bouwman   +3 more
doaj   +1 more source

Masked acute rejection of the graft kidney under the recovery of native kidneys in a patient who underwent simultaneous liver and kidney transplantation

IJU Case Reports, 2020
Introduction Simultaneous liver and kidney transplantation is a life‐saving procedure for patients with liver failure and irreversible renal dysfunction.
Kodai Hattahara, Atsuro Sawada, Kaoru Sakai, Yuki Teramoto, Yuji Nakamoto, Hideaki Okajima, Toshinari Yamasaki, Takahiro Inoue, Osamu Ogawa, Takashi Kobayashi   +9 more
doaj   +1 more source

CORNEAL GRAFT REJECTION AFTER KERATOPLASTY [PDF]

, 2017
Corneal transplantation is a method of surgical treatment used to restore the optical and structural properties of the diseased cornea which is successfully performed for over 100 years.
S. V. Trufanov, A. M. Subbot, D. A. Krakhmaleva, E. P. Salovarova, S. A. Malozhen   +4 more
core   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Does rejection have a role in lymphocele formation post renal transplantation? A single centre experience

Indian Journal of Urology, 2010
Aim : To assess the relation of acute rejection with respect to lymphocele incidence and determine the effect of lymphocele with graft survival. Methods : The paper is a singlecenter retrospective data review of renal transplant recipients from 1980 to
Muthu Veeramani, Sashikant Mishra, Abraham Kurien, Arvind Ganpule, Ravindra Sabnis, Mahesh Desai   +5 more
doaj   +1 more source