Results 91 to 100 of about 1,877,396 (306)

Effect of urinary tract infection on the outcome of the allograft in patients with kidney transplantation [PDF]

open access: yesBrazilian Journal of Nephrology
Background: Urinary tract infections (UTIs) are the second most common cause of graft dysfunction, accounting for significant morbidity, and are associated with poor graft and patient survival.
Rahul Sai Gangula   +8 more
doaj   +1 more source

The mid dermis graft. An experimental study

open access: yes, 1973
It is possible in the baboon and also in the human not only to transplant a thin split thickness graft successfully, but to cut a second layer from the donor area and to transplant this mid dermis graft successfully as well.
Van Der Walt J.J., Malherbe W.D.F.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Graft and overall survival.

open access: yes, 2014
(A) Graft survival rates for the reoperation group and the non-reoperation group. p = 0.31(the log-rank test). (B) Overall survival rates for the reoperation group and the non-reoperation group. p = 0.59 (the log-rank test).
Kiyoshi Hasegawa (530886)   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Graft survival and prognostic factors of recycled autografts after limb salvage surgery in patients with sarcoma of the long bone: a systematic review and meta-analysis of individual participant data

open access: yesJournal of Orthopaedic Surgery and Research
Background Recycled autografts are widely used in limb salvage surgery for patients with long-bone defects due to bone sarcoma resection. Currently, there are limited number of studies to sufficiently estimate graft survival and its modes of failure ...
Jeerawan Klangjorhor   +8 more
doaj   +1 more source

The feasibility and applications of non-invasive cardiac output monitoring, thromboelastography and transit-time flow measurement in living-related renal transplantation surgery : results of a prospective pilot observational study [PDF]

open access: yes, 2014
Introduction: Delayed graft function (DGF) remains a significant and detrimental postoperative phenomenon following living-related renal allograft transplantation, with a published incidence of up to 15%. Early therapeutic vasodilatory interventions have
Imray, C. (Chris)   +15 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

open access: yes, 2019
BackgroundCurrently, patients receiving vascularized composite allotransplantation (VCA) grafts must take long-term systemic immunosuppressive therapy to prevent immunologic rejection.
Shari D. Lawson (6260786)   +21 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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