Results 101 to 110 of about 3,062,873 (386)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Repeat penetrating corneal transplantation in patients with keratoconus [PDF]
, 2011 To determine factors influencing penetrating corneal graft survival in patients receiving repeat grafts in the same eye after a failed first graft for keratoconus, a large cohort study was conducted from a national register of corneal grafts, in which ...
Coster, Douglas John +2 more
core +1 more source
Impact of Combinations of Donor and Recipient Ages and Other Factors on Kidney Graft Outcomes
Frontiers in Immunology, 2020 As the availability of kidneys for transplantation continues to be outpaced by its growing demand, there has been an increasing utilization of older deceased donors in the last decades. Considering that definition of factors that influence deceased donor
Maria Gerbase-DeLima +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Small bowel and liver/small bowel transplantation in children. [PDF]
, 1993 A clinical trial of intestinal transplantation was initiated at the University of Pittsburgh in May 1990. Eleven children received either a combined liver/small bowel graft (n = 8) or an isolated small bowel graft (n = 3).
Nour, B +4 more
core
Second cadaver kidney transplants: Improved graft survival in secondary kidney transplants using cyclosporin A [PDF]
, 1984 A total of 42 patients who failed prior renal transplantation underwent repeat cadaveric transplantation cyclosporin A and low dose immunosuppression. Patient survival at 1 year was 100 per cent.
Caine +7 more
core +1 more source
The predictive value of kidney allograft baseline biopsies for long-term graft survival.
Journal of the American Society of Nephrology, 2013 The effect of baseline histology and individual histologic lesions at the time of transplantation on long-term graft survival has been evaluated using different scoring systems, but the predictive capacity of these systems has not been adequately ...
K. De Vusser +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
The clinical significance of the arterial ketone body ratio as an early indicator of graft viabilityin human liver transplantation [PDF]
, 1991 Arterial ketone body ratio (AKBR) was measured sequentially in 84 liver transplantations (OLTx). These transplantation procedures were classified into 3 groups with respect to graft survival and patient condition at the end of the first month (Group A ...
Asonuma, K +8 more
core +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source