Results 101 to 110 of about 315,322 (362)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Results of the kidney transplant programme at the University Clinical Centre of the Republic of Srpska from 2010 to 2018 [PDF]

Scripta Medica, 2019
Background: Kidney transplantation is the best treatment for patients with end-stage renal disease (ESRD). The aim of the study was to show the results of kidney transplantation performed in the University Clinical Centre of the Republic of Srpska in the
Grujičić Milorad, Žigić Milan, Maksić Milanko, Hajder Slobodan, Golić Darko, Gašić Branislav, Rakanović Dragan, Vasić Novak, Laganin Nataša, Roljić Zoran, Stajčić Ljubomir, Mišković Mirjana, Mićić-Zrnić Dubravka, Topić Goran, Đajić Vlado   +14 more
doaj  

O-34 PATIENT AND GRAFT SURVIVAL IN RECIPIENTS OF DE NOVO SIMULTANEOUS LIVER-KIDNEY TRANSPLANTATION

, 2023
Agustina Martínez Garmendia, Marlene Padilla, Tomás Fescina, María Cora Giordani, Gustavo Greloni, Rosana Groppa, Nora Imperialii, Paola Casciato, Sebastián Marciano   +8 more
openalex   +1 more source

Pretransplant BMI Significantly Affects Perioperative Course and Graft Survival after Kidney Transplantation: A Retrospective Analysis [PDF]

, 2022
Małgorzata Dobrzycka, Beata Bzoma, Ksawery Bieniaszewski, Alicja Dębska‐Ślizień, Jarek Kobiela   +4 more
openalex   +1 more source

Graft survival in pediatric liver transplantation

Journal of Pediatric Surgery, 2001
Liver transplantation is standard therapy for children with a variety of liver diseases. The current shortage of organ donors has led to aggressive use of reduced or split grafts and living-related donors to provide timely liver transplants to these children.
Miami, Florida, Gainesville, Florida ( host institution ), Langham, Max R. ( author ), Tzakis, Andreas G. ( author ), Gonzalez-Peralta, Regino ( author ), Thompson, John F. ( author ), Rosen, Charles B. ( author ), Nery, Jose R. ( author ), Reed, Alan I. ( author ), Ruiz, Philip ( author ), VanderWerf, Willem J. ( author ), Hemming, Alan ( author ), Howard, Richard J. ( author )   +12 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cost of lifetime immunosuppression coverage for kidney transplant recipients. [PDF]

, 2008
On January 1, 2000, Medicare extended the coverage of immunosuppression medications from 3 years to life for elderly and disabled kidney transplant recipients.
Page, Timothy F, Woodward, Robert
core   +1 more source

Prolonged Allogeneic Islet Graft Survival by Protoporphyrins

Cell Transplantation, 2005
Transplantation of islets of Langerhans in patients with type 1 diabetes allows for improved metabolic control and insulin independence. The need for chronic immunosuppression limits this procedure to selected patients with brittle diabetes.
Pileggi, Antonello, Molano, R Damaris, Berney, Thierry, Ichii, Hirohito, San Jose, Sergio, Zahr, Elsie, Poggioli, Raffaella, Linetsky, Elina, Ricordi, Camillo, Inverardi, Luca   +9 more
openaire   +5 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Long-term cardiac survival after reoperative coronary artery bypass grafting [PDF]

, 2003
L. Noyez, Frans M. van Eck
openalex   +1 more source