Results 101 to 110 of about 308,193 (309)

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Hepatic retransplantation in cholestatic liver disease: Impact of the interval to retransplantation on survival and resource utilization [PDF]

, 1999
The aim of our study was to quantitatively assess the impact of hepatic retransplantation on patient and graft survival and resource utilization. We studied patients undergoing hepatic retransplantation among 447 transplant recipients with primary ...
Benson, JT, Crippin, JS, Dickson, ER, Evans, RW, Kim, WR, Klintmalm, GBG, Krom, RAF, Malinchoc, M, Poterucha, JJ, Rakela, J, Starzl, TE, Therneau, TM, Wiesner, RH   +12 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

High-risk corneal allografts : A therapeutic challenge [PDF]

, 2016
Peer reviewedPublisher ...
Forrester, John V, Griffith, May, Kuffová, Lucia, Rajendran, Vijayalakshmi, Yu, Tian   +4 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Modeling Long-Term Graft Survival With Time-Varying Covariate Effects: An Application to a Single Kidney Transplant Centre in Johannesburg, South Africa

Frontiers in Public Health, 2019
Objectives: Patients' characteristics that could influence graft survival may also exhibit non-constant effects over time; therefore, violating the important assumption of the Cox proportional hazard (PH) model.
Okechinyere J. Achilonu, June Fabian, Eustasius Musenge   +2 more
doaj   +1 more source

Graft survival in pediatric liver transplantation

Journal of Pediatric Surgery, 2001
Liver transplantation is standard therapy for children with a variety of liver diseases. The current shortage of organ donors has led to aggressive use of reduced or split grafts and living-related donors to provide timely liver transplants to these children.
Miami, Florida, Gainesville, Florida ( host institution ), Langham, Max R. ( author ), Tzakis, Andreas G. ( author ), Gonzalez-Peralta, Regino ( author ), Thompson, John F. ( author ), Rosen, Charles B. ( author ), Nery, Jose R. ( author ), Reed, Alan I. ( author ), Ruiz, Philip ( author ), VanderWerf, Willem J. ( author ), Hemming, Alan ( author ), Howard, Richard J. ( author )   +12 more
openaire   +3 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Deceased donor renal transplantation at army hospital research and referral: Our experience

Indian Journal of Urology, 2013
Context: In India, there are a large number of end-stage renal disease (ESRD) patients waiting for renal transplant. Deceased donor organ transplantation (DDOT) is the possible solution to bridge the disparity between organ supply and demand. The concept
Yogesh Kumar Swami, Dharam Vir Singh, Sanjay K Gupta, Aditya A Pradhan, Yajvender P. S. Rana, Sandeep Harkar, M Shafi Wani   +6 more
doaj   +1 more source