AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
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Parkinson's Disease Cell Transplantation Therapy: A New Dawn With Pluripotent Stem Cell-Based Therapy. [PDF]
Nakanishi E +4 more
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Single–atom iron anchored on nitrogen–doped porous biochar exhibited ultra–efficient performance, exceptional environmental resilience, and integrated adsorption–oxidation functionality. The multifunctional architecture of the support and the unparalleled reactivity of single–atom iron underpinned the cooperative adsorption and oxidation of As(III ...
Tao Sun +8 more
wiley +1 more source
Melioidosis Presenting as a Mycotic Aneurysm of the Aortic Arch in a Patient With Pyrexia of Unknown Origin: A Case Report. [PDF]
Fenn BN +4 more
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First Experience with [<sup>18</sup>F]FAZA PET Imaging in Kidney Allograft Dysfunction. [PDF]
Mirshahvalad SA +9 more
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Primary Angiosarcoma of the Abdominal Aorta Following Endovascular Aneurysm Repair Mimicking Vascular Graft Infection. [PDF]
Wehmann M +4 more
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Macrophage metabolic reprogramming in organ transplantation: mechanisms, transplant outcomes, and therapeutic implications. [PDF]
Chen S, Kong D, Nian Y, Wang Z, Zheng H.
europepmc +1 more source
Descending aortic bypass for middle aortic syndrome due to Takayasu arteritis: A case report. [PDF]
Shibahara H +4 more
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Endovascular exclusion of an aortobronchial fistula 38 years following a blunt thoracic aortic injury. [PDF]
Lian T +4 more
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Graft Uptake in Burns: Clinical Audit and the Impact of Perioperative Interventions
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