Results 101 to 110 of about 234,176 (365)

Instant determination of the potential biomarker heparan sulfate in human plasma by a mix-and-read fluorescence assay [PDF]

arXiv, 2017
Heparan sulfate (HS) is a linear, polydisperse sulfated polysaccharide belonging to the glycosaminoglycan family. HS proteoglycans are ubiquitously found at the cell surface and extracellular matrix in animal species. HS is involved in the interaction with a wide variety of proteins and the regulation of many biological activities.
arxiv  

Multiple species animal movements: network properties, disease dynamic and the impact of targeted control actions [PDF]

arXiv, 2021
Infectious diseases in livestock are well-known to infect multiple hosts and persist through the combination of within- and between-host transmission pathways. Uncertainty remains about the epidemic consequences of the disease being introduced on farms with more than one susceptible host.
arxiv  

The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation [PDF]

, 2016
The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert regulatory and suppressive roles over the immune system.
Balsalobre, Pascual, Bento, Leyre, Bosch-Vizcaya, Anna, Brunet, Salut, Buces, Elena, Buño, Ismael, Cámara, Rafael de la, Díez-Martín, José L., Espigado, Ildefonso, Gallardo, David, Gayoso, Jorge, González Rivera, Milagros, Guillem, Vicent, Gónzalez, Marcos, Jiménez-Velasco, Antonio, Kwon, Mi, Martín-Antonio, Beatriz, Martínez, Carmen, Martínez-Laperche, Carolina, Nieto, José B., Noriega, Victor, Pion, Marjorie, Rojas-Contreras, Rafael, Sampol, Antonia, Serrano, David, Solano, Carlos, Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH), Sánchez-Hernández, Noemí, Urbano Ispizua, Álvaro, Vallejo, Carlos   +29 more
core   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Broadening of coreceptor usage by human immunodeficiency virus type 2 does not correlate with increased pathogenicity in an in vivo model. [PDF]

, 2000
The pathogenic properties of four primary human immunodeficiency virus type 2 (HIV-2) isolates and two primary HIV-2 biological clones were studied in an in vivo human-to-mouse chimeric model.
Boers, P.H.M. (Patrick), Ende, M.E. (Marchina) van der, Gruters, R.A. (Rob), Guillon, C. (Christophe), Osterhaus, A.D.M.E. (Albert), Racz, P., Schutten, M. (Martin), Tenner-Racz, K.   +7 more
core   +3 more sources

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate [PDF]

, 2013
Different types of graft-versus-host disease prophylaxis have been proposed in the setting of reduced intensity and non-myeloablative allogeneic stem cell transplantation.
Caballero, Dolores, Cabrero, Mónica, López Corral, Lucía, Martino, Rodrigo, Martínez, Carmen, Márquez Malaver, Francisco J., Parody, Rocío, Pérez Simón, José Antonio, Sierra, Jordi, Solano, Carlos, Valcárcel, D., Vázquez, Lourdes   +11 more
core   +1 more source

Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts

Advanced Materials Technologies, EarlyView.
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez, Maxime‐Emmanuel Comtois‐Bona, Antony El‐Khoury, Sergio David Garcia Schejtman, Aidan Macadam, Juan‐David Figueroa‐Alegria, Jesus M. Calderon‐Torres, Irene Guzmán‐Soto, Marc Ruel, Erik J. Suuronen, Marcelo Muñoz, Emilio I. Alarcon   +11 more
wiley   +1 more source

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation [PDF]

, 2011
Host macrophages protect against graft-versus-host disease in part by engulfing donor T cells and inhibiting their ...
Abe, Allavena, Alyea, Andrew Chow, Banovic, Bartocci, Beilhack, Bishop, Blazar, Blazar, Blazar, Bogunovic, Burnett, Cecchini, Chen Liu, Chitu, Collin, Cooke, Dai, Daigo Hashimoto, Dreger, Drobyski, Duffner, E. Richard Stanley, Ehlenberger, Facon, Felix, Florent Ginhoux, Fraser, Garcia, Ginhoux, Ginhoux, Ginhoux, Haniffa, Helft, Hill, Hill, Hume, Ide, Jasperson, Jenq, Jordi C. Ochando, Koyama, Krenger, Krenger, Lin, MacDonald, Maris, Marylene Leboeuf, Matozaki, Melanie Greter, Mempel, Menke, Merad, Merad, Mielcarek, Miller, Miriam Merad, Na, Namba, Nemunaitis, Nico van Rooijen, Okamoto, Panoskaltsis-Mortari, Paul S. Frenette, Pavletic, Peggs, Peter S. Heeger, Pollard, Rabinowe, Rozemuller, Shlomchik, Sorror, Sudo, Tacke, Takai, Takanori Teshima, Takenaka, Teshima, van Besien, Van Rooijen, Wiktor-Jedrzejczak, Wing-Hong Kwan, Wynn, Yoshida, Yuya Kunisaki, Yvonne Saenger, Zhang, Zhang   +88 more
core   +4 more sources

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

Advanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang, Hui Xue, Xiaohui Zhu, Dong Lin, Zheng Chen, Xin Dong, Junru Chen, Mingchen Shi, Yuchao Ni, Jonathan Cao, Rebecca Wu, Connie Kang, Xinyao Pang, Francesco Crea, Yen‐Yi Lin, Colin C. Collins, Martin E. Gleave, Abhijit Parolia, Arul Chinnaiyan, Christopher J. Ong, Yuzhuo Wang   +20 more
wiley   +1 more source