Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graft-versus-host disease [PDF]
Haematologica, 2010 Background Multipotent mesenchymal stromal cells suppress T-cell function in vitro, a property that has underpinned their use in treating clinical steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation ...
Melinda E. Christensen +8 more
doaj +2 more sources
B-cell involvement in chronic graft-versus-host disease
Haematologica, 2008 Chronic graft-versus-host disease is a serious complication in long-term survivors of allogeneic hematopoietic stem cell transplantation, with several organ systems affected.
Rick Kapur +2 more
doaj +2 more sources
Chronic graft-versus-host disease – the role of dermatological treatment [PDF]
Przegląd Dermatologiczny, 2017 Introduction . The number of allogeneic haematopoietic stem cell transplantations is increasing year by year. The most common long-term complication is chronic graft-versus-host disease, with skin involvement noted in over 90% of cases. Objective . To
Magdalena Żychowska +3 more
doaj +2 more sources
Patient-reported outcomes and health status associated with chronic graft-versus-host disease
Haematologica, 2018 Chronic graft-versus-host disease occurs in 20–50% of allogeneic hematopoietic cell transplant survivors. We surveyed patients about their quality of life, symptoms, health status, comorbid conditions and medications.
Stephanie J. Lee +8 more
doaj +3 more sources
Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review [PDF]
Anais Brasileiros de Dermatologia, 2016 Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease.
Cesar Daniel Villarreal Villarreal +3 more
doaj +3 more sources
Post-transplant cyclophosphamide versus anti-thymocyte globulin as graft- versus-host disease prophylaxis in haploidentical transplant [PDF]
Haematologica, 2017 Severe graft-versus-host disease is a major barrier for non-T-cell-depleted haploidentical stem cell transplantation. There is no consensus on the optimal graft-versus-host disease prophylaxis.
Annalisa Ruggeri +17 more
doaj +2 more sources
Ocular Graft versus Host Disease
Vision Pan-America, 2015 Allogeneic hematopoietic stem cell transplantation is considered the standard of care for hematological and lymphoid malignancies. One of the complications associated to this therapy is an immune-mediated reaction known as graft versus host disease with ...
Paulo E.C. Dantas
doaj +2 more sources
Novel regulatory therapies for prevention of Graft-versus-host disease
BMC Medicine, 2012 Graft-versus-host disease is one of the major transplant-related complications in allogeneic hematopoietic stem cell transplantation. Continued efforts have been made to prevent the occurrence of severe graft-versus-host disease by eliminating or ...
Leventhal Joseph +4 more
doaj +2 more sources
Brain, 2010 A major obstacle of allogeneic haematopoietic stem cell transplantation is graft-versus-host disease, an immune-mediated disorder that affects multiple tissues and organs with varying severity. Neurological complications of acute and chronic graft-versus-
Oliver Grauer, Daniel Wolff, H Bertz
exaly +2 more sources
Skin-Limited Graft-versus-Host Disease after Pancreatic Transplantation
Case Reports in Transplantation, 2017 Introduction. The phenomenon of graft-versus-host disease, a solid organ transplant recipient, is a rare development with a very poor prognosis. Case Presentation.
Muneeb Ilyas +5 more
doaj +2 more sources