Chronic graft versus host disease (GVHD) is a less frequently seen disease that occurs post solid organ or bone marrow transplantation. Chronic GVHD occurring post blood transfusion is an even more uncommon disease.
Pushpa Kodipalya Ramakrishnaiah +3 more
doaj +1 more source
Cumulative incidence of tuberculosis in allogeneic hematopoietic stem cell transplantation recipients with and without chronic graft-versus-host-disease. [PDF]
Extensive chronic GVHD was associated with the development of TB (P = 0.003) There is a 4.89 ± 1.32% probability of having TB disease at 1000 days after allogeneic HSCT for extensive chronic GVHD and 1.42 ± 0.50% for limited or without chronic GVHD ...
Dong-Gun Lee (3826297) +18 more
core +1 more source
Background A variety of immune pathways can lead to graft-versus-host disease. A better understanding of the type of immune response causing graft-versus-host disease in defined clinical hematopoietic stem cell transplant settings is required to inform ...
Katie Matthews +10 more
doaj +1 more source
Progress in acute graft versus host disease [PDF]
Purpose of review The aim of this article is to highlight both experimental and clinical studies contributing to our present understanding of acute graft versus host disease. Recent findings New cellular players and new molecules in induction, modulation
Holler, Ernst
core +1 more source
Combination of pleuroparenchymal fibroelastosis with non-specific interstitial pneumonia and bronchiolitis obliterans as a complication of hematopoietic stem cell transplantation — Clues to a potential mechanism [PDF]
Pleuroparenchymal fibroelastosis (PPFE) is a newly described entity of interstitial lung disease,which has been recently recognized as a rare complication of bone marrow transplantation.
Bychkov, Andrey +11 more
core +2 more sources
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki +12 more
core +1 more source
Backgrounds of patients with acute gastrointestinal graft-versus-host disease or infectious colitis. [PDF]
Backgrounds of patients with acute gastrointestinal graft-versus-host disease or infectious colitis.
Gota Sudo (5570936) +8 more
core +1 more source
Improved survival after acute graft-versus-host disease diagnosis in the modern era
A cute graft-versus-host disease remains a major threat to a successful outcome after allogeneic hematopoietic cell transplantation. While improvements in treatment and supportive care have occurred, it is unknown whether these advances have resulted in ...
Hanna J. Khoury +46 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

