Results 61 to 70 of about 332,330 (302)

Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis

Haematologica, 2019
The use of antihuman T-lymphocyte immunoglobulin in the setting of transplantation from an HLA-matched related donor is still much debated. Acute and chronic graft-versus-host disease are the main causes of morbidity and mortality after allogeneic ...
Marie Robin, Sylvie Chevret, Linda Koster, Christine Wolschke, Ibrahim Yakoub-Agha, Jean Henri Bourhis, Patrice Chevallier, Jan J. Cornelissen, Péter Reményi, Johan Maertens, Xavier Poiré, Charles Craddock, Gérard Socié, Maija Itälä-Remes, Harry C. Schouten, Tony Marchand, Jakob Passweg, Didier Blaise, Gandhi Damaj, Zubeyde Nur Ozkurt, Tsila Zuckerman, Thomas Cluzeau, Hélène Labussière-Wallet, Jörg Cammenga, Donal McLornan, Yves Chalandon, Nicolaus Kröger   +26 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy

Haematologica, 2016
Due to the lack of specificity for tumor antigens, allogeneic T-cell therapy is associated with graft-versus-host disease. Enhancing the anti-tumor specificity while reducing the graft-versus-host disease risk of allogeneic T cells has remained a ...
Angelika Holler, Mathias Zech, Sara Ghorashian, Rebecca Pike, Alastair Hotblack, Pedro Veliça, Shao-An Xue, Ronjon Chakraverty, Emma C. Morris, Hans J. Stauss   +9 more
doaj   +1 more source

Selective allodepletion to improve anti-viral and anti-leukaemic responses after haploidentical transplantation [PDF]

, 2009
Immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical SCT, but infection and leukaemic relapse remain problematic.
Samarasinghe, S, Samarasinghe, S.
core  

Progress in acute graft versus host disease

, 2007
Purpose of review The aim of this article is to highlight both experimental and clinical studies contributing to our present understanding of acute graft versus host disease. Recent findings New cellular players and new molecules in induction, modulation
Holler, Ernst
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Combination of pleuroparenchymal fibroelastosis with non-specific interstitial pneumonia and bronchiolitis obliterans as a complication of hematopoietic stem cell transplantation — Clues to a potential mechanism

, 2019
Pleuroparenchymal fibroelastosis (PPFE) is a newly described entity of interstitial lung disease,which has been recently recognized as a rare complication of bone marrow transplantation.
Bychkov, Andrey, Kadota, Jun-ichi, Mari Yamasue, Junya Fukuoka, Fukuoka, Junya, Yoshiaki Zaizen, Oo, Zun Pwint, Zaizen, Yoshiaki, Yamasue, Mari, Zun Pwint Oo, Andrey Bychkov, Jun-ichi Kadota   +11 more
core   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Sensitivity of changes in chronic graft-versus-host disease activity to changes in patient-reported quality of life: results from the Chronic Graft-versus-Host Disease Consortium

Haematologica, 2011
Background The 2005 National Institute of Health Chronic Graft-versus-Host Disease Consensus Conference recommended collection of patient-reported outcomes in clinical trials on chronic graft-versus-host disease.
Joseph Pidala, Brenda F. Kurland, Xiaoyu Chai, Georgia Vogelsang, Daniel J. Weisdorf, Steven Pavletic, Corey Cutler, Navneet Majhail, Stephanie J. Lee   +8 more
doaj   +1 more source