Results 11 to 20 of about 7,285,650 (306)

B-cell involvement in chronic graft-versus-host disease

open access: yesHaematologica, 2008
Chronic graft-versus-host disease is a serious complication in long-term survivors of allogeneic hematopoietic stem cell transplantation, with several organ systems affected.
Rick Kapur   +2 more
doaj   +2 more sources

Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graft-versus-host disease [PDF]

open access: yesHaematologica, 2010
Background Multipotent mesenchymal stromal cells suppress T-cell function in vitro, a property that has underpinned their use in treating clinical steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation ...
Melinda E. Christensen   +8 more
doaj   +2 more sources

NOTCH and Graft-Versus-Host Disease [PDF]

open access: yesFrontiers in Immunology, 2018
In allogeneic hematopoietic stem cell transplantation, which is the major curative therapy for hematological malignancies, T cells play a key role in the development of graft-versus-host disease (GvHD).
Mauro Di Ianni   +15 more
doaj   +5 more sources

Patient-reported outcomes and health status associated with chronic graft-versus-host disease [PDF]

open access: yesHaematologica, 2018
Chronic graft-versus-host disease occurs in 20–50% of allogeneic hematopoietic cell transplant survivors. We surveyed patients about their quality of life, symptoms, health status, comorbid conditions and medications.
Stephanie J. Lee   +8 more
doaj   +2 more sources

Chronic graft-versus-host disease – the role of dermatological treatment [PDF]

open access: yesPrzegląd Dermatologiczny, 2017
Introduction . The number of allogeneic haematopoietic stem cell transplantations is increasing year by year. The most common long-term complication is chronic graft-versus-host disease, with skin involvement noted in over 90% of cases. Objective . To
Magdalena Żychowska   +3 more
doaj   +2 more sources

Ocular Graft versus Host Disease

open access: yesVision Pan-America, 2015
Allogeneic hematopoietic stem cell transplantation is considered the standard of care for hematological and lymphoid malignancies. One of the complications associated to this therapy is an immune-mediated reaction known as graft versus host disease with ...
Paulo E.C. Dantas
doaj   +2 more sources

Novel regulatory therapies for prevention of Graft-versus-host disease [PDF]

open access: yesBMC Medicine, 2012
Graft-versus-host disease is one of the major transplant-related complications in allogeneic hematopoietic stem cell transplantation. Continued efforts have been made to prevent the occurrence of severe graft-versus-host disease by eliminating or ...
Leventhal Joseph   +4 more
doaj   +3 more sources

Skin-Limited Graft-versus-Host Disease after Pancreatic Transplantation

open access: yesCase Reports in Transplantation, 2017
Introduction. The phenomenon of graft-versus-host disease, a solid organ transplant recipient, is a rare development with a very poor prognosis. Case Presentation.
Muneeb Ilyas   +5 more
doaj   +2 more sources

Comparison of alemtuzumab, anti-thymocyte globulin, and post-transplant cyclophosphamide for graft-versus-host disease and graft-versus-leukemia in murine models.

open access: yesPLoS ONE, 2021
Graft-versus-host disease is a major complication after allogeneic hematopoietic stem cell transplantation for hematological malignancies. Immunosuppressive drugs, such as anti-thymocyte globulin, alemtuzumab, and post-transplant cyclophosphamide, have ...
Kiyomi Mashima   +17 more
doaj   +1 more source

Graft-versus-host disease [PDF]

open access: yesBMJ Case Reports, 2010
This article presents the case of a 26-year-old man who was diagnosed with pneumatosis cystoides intestinalis, a rare consequence of colonic graft-versus-host disease, after CT imaging revealed free air tracking within the bowel wall and abdomen. His presentation with hiccups, abdominal and neck distension, along with diarrhoea was also unusual, and ...
Joel A, Newman   +4 more
openaire   +2 more sources

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