Results 141 to 150 of about 172,684 (356)

The role of graft T-cell size in patients receiving alemtuzumab serotherapy for non-malignant disorders: results of an institutional protocol

Scientific Reports
Although graft T cells assist in engraftment, mediate antiviral immune-reconstitution, and cause graft-versus-host disease, graft size is not determined by T-cell content of the graft.
Ambreen Pandrowala, Sanna Khan, Darshan Kataria, Manasa Kakunje, Varsha Mishra, Dhruv Mamtora, Sangeeta Mudaliar, Minnie Bodhanwala, Bharat Agarwal, Prashant Hiwarkar   +9 more
doaj   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

Ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation in a pediatric population

Hematology, Transfusion and Cell Therapy
Aim: To determine the prevalence of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation and to characterize the risk factors associated with its development in a pediatric population.
Cinthia Kim, Patricia Cabral Zacharias Serapicos, Cintia Monteiro Lustosa, Adriane da Silva Santos Ibanez, Victor Gottardello Zecchin, Lauro Augusto de Oliveira   +5 more
doaj   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

The role of Janus kinase signaling in graft-versus-host disease and graft versus leukemia [PDF]

, 2018
Choi, Jaebok, DiPersio, John F, Schroeder, Mark A, Staser, Karl   +3 more
core   +2 more sources

Kaplan–Meier method is inappropriate for estimating cumulative incidence of graft‐versus‐host disease in the presence of competing events [PDF]

, 2010
Marcos Borato Viana, Benigna Maria de Oliveira, Camila Silva Peres Cancela   +2 more
openalex   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Reprint of: B Cells in Chronic Graft-versus-Host Disease [PDF]

, 2015
Stefanie Sarantopoulos, Bruce R. Blazar, Corey Cutler, Jerome Ritz   +3 more
openalex   +1 more source

PEDOT:PSS—A Key Material for Bioelectronics

Advanced Science, EarlyView.
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez, David Pieter van der Laan, Mustafeez Bashir Shah, Liwen Wang, Erica Zeglio, Achilleas Savva   +5 more
wiley   +1 more source

Single Infusion of Donor Mononuclear Early Apoptotic Cells as Prophylaxis for Graft-versus-Host Disease in Myeloablative HLA-Matched Allogeneic Bone Marrow Transplantation: A Phase I/IIa Clinical Trial

, 2013
Dror Mevorach, Tsila Zuckerman, Inna Reiner, Avichai Shimoni, Simcha Samuel, Arnon Nagler, Jacob M. Rowe, Reuven Or   +7 more
openalex   +1 more source