Classical and Late‐Onset SOS/VOD After Allogeneic HSCT: A Japanese Transplant Registry Analysis
ABSTRACT Sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD) is a lethal complication of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). According to the 2016 European Society for Blood and Marrow Transplantation criteria, SOS/VOD is classified into classical SOS/VOD and late‐onset SOS/VOD, but their similarities and ...
Kyoko Masuda+20 more
wiley +1 more source
EFFECTS OF THYMECTOMY AND IRRADIATION ON GRAFT-VERSUS-HOST DISEASE
E.O. Field, J. E. Gibbs
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Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. [PDF]
Robert Korngold, Jonathan Sprent
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Some similarities between the neonatal thymectomy syndrome and graft-versus-host disease
J. F. A. P. Miller, J G Howard
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Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe+5 more
wiley +1 more source
Azithromycin for Prevention of Graft-Versus-Host Disease: A Randomized Placebo-Controlled Trial
Background: Allogeneic hematopoietic stem cell transplantation has been used widely to treat various types of malignant and non-malignant disorders. Graft-versus-host disease is one of the main complications of this procedure which is associated with ...
Maryam Barkhordar+4 more
doaj
Recovery of antibody production in human allogeneic marrow graft recipients: influence of time posttransplantation, the presence or absence of chronic graft-versus-host disease, and antithymocyte globulin treatment [PDF]
RP Witherspoon+10 more
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Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
wiley +1 more source
GRAFT-VERSUS-HOST DISEASE PRODUCED WITH WHOLE BLOOD
Seymour Levine, Masao Iwahara
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Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease [PDF]
R.S. Hill+7 more
openalex +1 more source