Results 241 to 250 of about 172,684 (356)

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

open access: yesArthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong   +13 more
wiley   +1 more source

Cotransplantation of Mesenchymal Stem Cells Might Prevent Death from Graft-versus-Host Disease (GVHD) without Abrogating Graft-versus-Tumor Effects after HLA-Mismatched Allogeneic Transplantation following Nonmyeloablative Conditioning

open access: hybrid, 2010
Frédéric Baron   +11 more
openalex   +1 more source

Gamma Irradiation of Poly(lactide‐co‐glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Clinical islet transplantation has long been investigated as a potential cure for type 1 diabetes (T1D), yet standard intrahepatic delivery leaves islets prone to an instant blood‐mediated inflammatory response. Herein, we investigated the design of microporous poly(D,l‐lactide‐co‐glycolide) (PLG) scaffolds for extrahepatic islet ...
Jessica L. King   +15 more
wiley   +1 more source

The mystique of organ transplantation [PDF]

open access: yes, 2005
Bach   +48 more
core   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

open access: yesBiotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen   +5 more
wiley   +1 more source

Incidence of fistulas following human pancreas transplantation [PDF]

open access: yes, 1987
Abendroth, D.   +3 more
core   +1 more source

Treatment of Graft-Versus-Host Disease After Liver Transplantation with Basiliximab Followed by Bowel Resection

open access: hybrid, 2003
S Sudhindran   +10 more
openalex   +1 more source

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