In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications
Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian+2 more
wiley +1 more source
Extracellular vesicles: a new frontier in diagnosing and treating graft-versus-host disease after allogeneic hematopoietic cell transplantation. [PDF]
Wu P+5 more
europepmc +1 more source
The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi+2 more
wiley +1 more source
Comparison of oral chronic graft-versus-host disease characteristics between patients with malignant and non-malignant hematopoietic disorders. [PDF]
Jiang Q+10 more
europepmc +1 more source
Reduction of graft-versus-host disease in neonatal Fl hybrid mice
Luisa DeGiorgi+3 more
openalex +2 more sources
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao+9 more
wiley +1 more source
Uncommon finding in a pulmonary graft versus host disease: A first report of Tsukamurella pneumonia in a pulmonary graft-versus-host disease. [PDF]
Bertuccio FR+13 more
europepmc +1 more source
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) is a curative treatment for sickle cell disease (SCD). However, barriers exist that prevent access to this treatment modality. Methods An IRB‐approved mixed‐method survey of barriers to HSCT in SCD was given to parents, caregivers, and adolescents obtaining care at the Children's of ...
Chibuzo Ilonze+4 more
wiley +1 more source
PTCy-based graft-versus-host disease prophylaxis for matched sibling donor allogeneic hematopoietic cell transplantation. [PDF]
Desai N+16 more
europepmc +1 more source
ABSTRACT Background Dyskeratosis congenita (DKC) is a genetic disorder frequently complicated by bone marrow failure (BMF). Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment option for BMF in DKC. However, late complications of DKC, especially pulmonary fibrosis (PF), pose significant challenges.
Takashi Koike+12 more
wiley +1 more source