Results 21 to 30 of about 172,684 (356)

Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults

Haematologica, 2016
We previously reported that bone marrow grafts from matched sibling donors resulted in best graft-versus-host disease-free, relapse-free survival at 1-year post allogeneic hematopoietic cell transplantation.
Rohtesh S. Mehta, Regis Peffault de Latour, Todd E DeFor, Marie Robin, Aleksandr Lazaryan, Aliénor Xhaard, Nelli Bejanyan, Flore Sicre de Fontbrune, Mukta Arora, Claudio G. Brunstein, Bruce R. Blazar, Daniel J. Weisdorf, Margaret L. MacMillan, Gerard Socie, Shernan G. Holtan   +14 more
doaj   +1 more source

Broadening of coreceptor usage by human immunodeficiency virus type 2 does not correlate with increased pathogenicity in an in vivo model. [PDF]

, 2000
The pathogenic properties of four primary human immunodeficiency virus type 2 (HIV-2) isolates and two primary HIV-2 biological clones were studied in an in vivo human-to-mouse chimeric model.
Boers, P.H.M. (Patrick), Ende, M.E. (Marchina) van der, Gruters, R.A. (Rob), Guillon, C. (Christophe), Osterhaus, A.D.M.E. (Albert), Racz, P., Schutten, M. (Martin), Tenner-Racz, K.   +7 more
core   +3 more sources

Predictive models for ocular chronic graft-versus-host disease diagnosis and disease activity in transplant clinical practice

Haematologica, 2015
Ocular chronic graft-versus-host disease is one of the most bothersome common complications following allogeneic hematopoietic stem cell transplantation.
Lauren M. Curtis, Manuel B. Datiles, Seth M. Steinberg, Sandra A. Mitchell, Rachel J. Bishop, Edward W. Cowen, Jacqueline Mays, John M. McCarty, Zoya Kuzmina, Filip Pirsl, Daniel H. Fowler, Ronald E. Gress, Steven Z. Pavletic   +12 more
doaj   +1 more source

Busulfan and melphalan as conditioning regimen for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia in first complete remission [PDF]

, 2011
BACKGROUND: Allogeneic hematopoietic stem cell transplantation with HLA-identical donors has been established for the treatment of acute myeloid leukemia patients for over 30 years with a cure rate of 50% to 60%.
AMIGO FILHO, José Ulysses, BUENO, Nadjanara Dorna, CHAMONE, Dalton de Alencar Fischer, CORACIN, Fabio Luiz, DULLEY, Frederico Luiz, SABOYA, Rosaura   +5 more
core   +2 more sources

Comparison of graft-versus-host disease-free, relapse-free survival according to a variety of graft sources: antithymocyte globulin and single cord blood provide favorable outcomes in some subgroups

Haematologica, 2016
Graft-versus-host disease-free relapse-free survival, which is defined as the absence of grade III–IV acute graft-versus-host disease, systemically treated chronic graft-versus-host disease, relapse, and death, is a novel, meaningful composite end point ...
Yoshihiro Inamoto, Fumihiko Kimura, Junya Kanda, Junichi Sugita, Kazuhiro Ikegame, Hideki Nakasone, Yasuhito Nannya, Naoyuki Uchida, Takahiro Fukuda, Kosuke Yoshioka, Yukiyasu Ozawa, Ichiro Kawano, Yoshiko Atsuta, Koji Kato, Tatsuo Ichinohe, Masami Inoue, Takanori Teshima   +16 more
doaj   +1 more source

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies. [PDF]

, 2015
Treatment of hematological malignant disorders has been improved over the last years, but high relapse rate mainly attributable to the presence of minimal residual disease still persists.
Biassoni, Biron, Björklund, Brodin, Bryceson, Burns, Campbell, Cooley, Cooper, Cooper, Curti, Davies, Di Santo, Di Santo, Farag, Fehniger, Fogler, Foley, Freud, Gasser, Gilfillan, Grimm, Guethlein, Herberman, Huntington, Joncker, Kiessling, Killig, King, Kröger, Lajoie, Lanier, Leong, Ljunggren, Lowe, Lundqvist, Mancusi, McQueen, Miller, Moretta, Moretta, Moretta, Nguyen, Oevermann, Ouyang, Perussia, Phillips, Romagnani, Romee, Rosenberg, Rosenberg, Rosenberg, Ruggeri, Santoni, Stabile, Stabile, Stern, Stringaris, Thielens, Torelli, Trinchieri, Trinchieri, Vago, Valés-Gómez, Venstrom, Vivier, Whitelaw, Zorn   +67 more
core   +1 more source

Chronic graft-versus-host disease: clinical presentation of multiple lesions of lichenoid and atrophic pattern [PDF]

Anais Brasileiros de Dermatologia, 2013
Graft-versus-host disease is observed mainly in recipients of hematopoietic cell transplantation and is expressed by cutaneous or systemic signals and symptoms. Graft-versus-host disease is clinically classified as acute or chronic.
Luiza Vasconcelos, Erica Cristina Vieira, Eliana Maria Minicucci, Ana Gabriela Salvio, Mair Pedro de Souza, Mariangela Esther Alencar Marques, Silvio Alencar Marques   +6 more
doaj   +1 more source

Comparable composite endpoints after HLA-matched and HLA-haploidentical transplantation with post-transplantation cyclophosphamide

Haematologica, 2017
Composite endpoints that not only encompass mortality and relapse, but other critical post-transplant events such as graft-versus-host disease, are being increasingly utilized to quantify survival without significant morbidity after allogeneic blood or ...
Shannon R. McCurdy, Yvette L. Kasamon, Christopher G. Kanakry, Javier Bolaños-Meade, Hua-Ling Tsai, Margaret M. Showel, Jennifer A. Kanakry, Heather J. Symons, Ivana Gojo, B. Douglas Smith, Maria P. Bettinotti, William H. Matsui, Amy E. Dezern, Carol Ann Huff, Ivan Borrello, Keith W. Pratz, Douglas E. Gladstone, Lode J. Swinnen, Robert A. Brodsky, Mark J. Levis, Richard F. Ambinder, Ephraim J. Fuchs, Gary L. Rosner, Richard J. Jones, Leo Luznik   +24 more
doaj   +1 more source

Alloreactivity: the Janus-face of hematopoietic stem cell transplantation [PDF]

, 2017
Differences in major and minor histocompatibility antigens between donor and recipient trigger powerful graft-versus-host reactions after allogeneic hematopoietic stem cell transplantation (HSCT).
Apperley, J. (Jane), Brand, R. (René), Cornelissen, J.J. (Jan), Dreger, P. (Peter), Duarte, R.F. (Rafael), Gratwohl, A. (Alois), Greinix, H.T. (H. T.), Kroeger, N. (Nicolaus), Lanza, F. (F.), Mc Grath, E. (E.), Nagler, A. (Arnon), Niederwieser, D. (Dietger), Snowden, J. (John), Sureda, A. (Anna)   +13 more
core   +1 more source

On the crossroad between tolerance and posttransplant lymphoma. [PDF]

, 1997
The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core   +1 more source