Results 41 to 50 of about 172,684 (356)

Etanercept for steroid-refractory acute graft-versus-host disease [PDF]

, 2017
Background: Acute graft-versus-host disease (aGVHD) is an important complication of allogeneic stem cell transplantation (alloSCT). High dose glucocorticosteroids, are currently recommended as first-line treatment for grade II-IV ...
Broers, A.E.C. (Annoek), Cornelissen, J.J. (Jan), Jong, C.N. (Cornelis) de, Klerk, C.P.W. (Clara P. W.), Klift, M. (Marjolein) van der, Saes, L. (Lotte)   +5 more
core   +1 more source

Novel elucidation and treatment of pancreatic chronic graft-versus-host disease in mice [PDF]

, 2018
Chronic graft-versus-host disease (cGVHD) is a severe complication of allogeneic haematopoietic stem cell transplantation. There is a growing understanding of cGVHD, and several effective therapies for cGVHD have been reported.
Kawakami, Yutaka, Mukai, Shin, Ogawa, Yoko, Tsubota, Kazuo, Urano, Fumihiko   +4 more
core   +3 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Novel regulatory therapies for prevention of Graft-versus-host disease

BMC Medicine, 2012
Graft-versus-host disease is one of the major transplant-related complications in allogeneic hematopoietic stem cell transplantation. Continued efforts have been made to prevent the occurrence of severe graft-versus-host disease by eliminating or ...
Leventhal Joseph, Huang Yiming, Xu Hong, Goode Idona, Ildstad Suzanne T   +4 more
doaj   +1 more source

The pathology of bone marrow transplantation in Hong Kong Chinese [PDF]

, 1996
The pathological lesions found in 68 successfully engrafted patients with human leucocyte antigen-matched sibling-related bone marrow transplants werereviewed retrospectively.
Chan, KW, Chiu, EKW, Ng, IOL, Shek, TWH
core  

Chimerism after organ transplantation [PDF]

, 1997
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ, Fung, JJ, Murase, N, Rao, AS, Starzl, TE, Thomson, AW, Trucco, M   +6 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Overlap subtype of chronic graft-versus-host disease is associated with an adverse prognosis, functional impairment, and inferior patient-reported outcomes: a Chronic Graft-versus-Host Disease Consortium study

Haematologica, 2012
Background The National Institutes of Health Consensus Conference proposed the term “overlap” graft-versus-host disease to describe the situation when both acute and chronic graft-versus-host disease are present.Design and Methods We examined whether the
Joseph Pidala, Georgia Vogelsang, Paul Martin, Xiaoyu Chai, Barry Storer, Steven Pavletic, Daniel J. Weisdorf, Madan Jagasia, Corey Cutler, Jeanne Palmer, David Jacobsohn, Sally Arai, Stephanie J. Lee   +12 more
doaj   +1 more source

Graft-versus-host disease affecting oral cavity: a review [PDF]

, 2015
Graft versus host disease (GVHD) is one of the most frequent and serious complications of hematopoietic stem cell transplantation, and is regarded as the leading cause of late mortality unrelated to the underlying malignant disease. GVHD is an autoimmune
Bagán Sebastián, José Vicente, Jiménez Soriano, Yolanda, Margaix Muñoz, María, Poveda Roda, Rafael, Sarrión Pérez, María Gracia   +4 more
core   +1 more source

Chronic graft-versus-host disease

Biology of Blood and Marrow Transplantation, 2003
Chronic graft-versus-host disease (GVHD) remains a vexing and dangerous complication of allogeneic stem cell transplantation. Mild forms of chronic GVHD are often manageable with local or low-dose systemic immunosuppression and do not affect long-term survival.
Lee, Stephanie J., Vogelsang, Georgia, Flowers, Mary E.D.   +2 more
openaire   +2 more sources