Results 201 to 210 of about 8,034,026 (305)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Histopathologic Grading of Acute Cutaneous Graft-vs-Host Disease and Nonrelapse Mortality.

JAMA Dermatol
Chen J, Raymundo C, Martinez A, Lee SJ, Stevenson PA, Shinohara MM.   +5 more
europepmc   +1 more source

Performance of Treatment Response Assessment at Day 7 by Baseline Acute Graft-versus-Host Disease Severity. [PDF]

Transplant Cell Ther
Louloudis IE, Chen YB, Spyrou N, Alousi A, Katsivelos N, Ayuk F, Weber D, Hogan WJ, Etra AM, Qayed M, Aguayo-Hiraldo P, Akahoshi Y, Malki MMA, Bolaños-Meade J, Chanswangphuwana C, Diniz M, Eder M, Hexner E, Kitko CL, Kraus S, Merli P, Olson T, MacMillan ML, Pidala J, Reshef R, Schechter T, Wölfl M, Baez J, Eng G, Gleich S, Young R, Nakamura R, Ferrara JLM, Levine JE.   +33 more
europepmc   +1 more source

Mapping Tumor Recurrence and Metastasis With Pan‐Cancer Multi‐Omics

Med Research, EarlyView.
Tumor recurrence and metastasis arise from the interaction of shared evolutionary programs and context‐dependent modifiers. Clonal evolution, including genomic instability, subclonal selection, and treatment pressure, interacts with reversible cell‐state plasticity involving partial EMT, stemness, and dormancy, whereas immune escape, stromal remodeling,
Wenjun Meng, Ruicen Li, Xiaoli Mu, Xiaolong Tang, Yuxi Luo, Yingying Lei, Jinghong Xian, Guiyi Ji, Yihao Liu, Chenyu Huo, Sihan Li, Yalun Li, Jiadi Gan, Weimin Li   +13 more
wiley   +1 more source

Study protocol: Close Assessment and Testing for Chronic Graft-vs.-Host disease (CATCH). [PDF]

PLoS One
Pidala J, Carpenter PA, Onstad L, Pavletic SZ, Hamilton BK, Chen GL, Farhadfar N, Hall M, Lee SJ.   +8 more
europepmc   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Outcomes of Importance to Patients Living With Cutaneous Chronic Graft-vs-Host Disease.

JAMA Dermatol
Baumrin E, Cronholm PF, Kearney MD, Mengesha M, Cesar LG, Keddem S, Schapira MM, Lee SJ, Loren AW, Gelfand JM.   +9 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source