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Mucosal graft‐vs‐host disease

Oral Diseases, 2007
Graft‐vs‐host disease (GVHD) is a serious complication of hematopoietic stem cell transplantation (HSCT). Indications for HSCT have greatly expanded, and more patients are undergoing HSCT today than ever before. In addition, the options for immunosuppressive therapy for both prevention and treatment of GVHD have also expanded.
J, Lew, J A, Smith
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Ocular Graft vs. Host Disease

The Ocular Surface, 2005
Acute graft vs host disease (GVHD) is thought to be mainly a Th1 inflammatory-mediated process, whereas chronic GVHD involves primarily Th2 inflammation. To elucidate new strategies for the treatment and prevention of ocular GVHD, it is important to understand the pathophysiologic connection between systemic and organ-specific acute and chronic GVHD ...
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Syngeneic Graft-vs-Host Disease

Archives of Dermatology, 1987
Graft-vs-hostD) can be a lethal complication of bone marrow transplantation. The acute form of the disease most often occurs by day 60 after transplant and may affect any or all of three major target organs, namely, skin, liver, and gastrointestinal ointestinal tract.1y ute GVHD terized by a dermatitis that begins as a pruritic macular exanthem on the ...
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Life-threatening graft-vs-host disease

Clinics in Dermatology, 2005
Hematopoietic stem cell transplant (SCT) is considered standard therapy for a variety of malignant and nonmalignant diseases. Graft-versus-host disease (GVHD) still represents today a major complication of hematopoietic SCT. Two types of GVHD have traditionally been recognized on the basis of the time of onset following transplantation, distinct ...
Erich, Vargas-Díez   +3 more
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Severity of acute gastrointestinal graft‐vs‐host disease is associated with incidence of bloodstream infection after adult allogeneic hematopoietic stem cell transplantation

Transplant Infectious Disease, 2019
Infections are the most common cause of non‐relapse mortality in adult allogeneic hematopoietic stem cell transplant (allo HSCT) recipients. Acute gastrointestinal graft‐vs‐host disease (GI GVHD) often leads to friable mucosa as well as treatment ...
Anita Modi   +3 more
semanticscholar   +1 more source

Graft-vs-Host Disease

2000
The transplantation of healthy hematopoietic stem cells into a patient with aplastic anemia or leukemia is potentially curative therapy, but the development of acute graftvs-host disease (GVHD), which often occurs even when the donor and recipient are siblings fully matched at the human leukocyte antigen (HLA) loci, significantly limits survival.The ...
Thomas R. Spitzer, Robert Sackstein
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The association between the incidence of intestinal graft‐vs‐host disease and antibiotic use after allogeneic hematopoietic stem cell transplantation

Clinical Transplantation, 2018
Intestinal microbiota plays an important role in the regulation of allogeneic immune reaction after allogeneic hematopoietic stem cell transplantation (allo‐SCT).
Daisuke Hidaka   +14 more
semanticscholar   +1 more source

Graft-vs-host disease

Bone Marrow Transplantation, 2005
JLM Ferrara, KR Cooke and HJ Deeg (eds) Third edition, 2005. Marcel Dekker, New York, NY, USA, ISBN: 0-8247-5472-7, 645pp.
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[Graft vs host disease].

Pathologie-biologie, 2006
Graft vs host disease is a serious immunological complication of allogeneic haematopoietic cell transplantation, leading to a significant morbidity and mortality. It occurs when donor T lymphocyte react to foreign host cells. The physiopathology is a more complex process implicating host tissues damage caused by the conditioning regimen, cytokines ...
V, Moalic, C, Ferec
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Approaches to graft‐vs‐host disease

Pediatric Transplantation, 2005
Abstract:  Graft‐vs‐host disease (GVHD) is one of the most difficult problems in stem cell transplantation. It is best considered in the context of the normal immune response. The role of the immune system is to identify and eliminate foreign antigens.
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