Results 41 to 50 of about 271,561 (299)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Starch Grafted with Polyacrylic Acid as a Renewable Alternative for Fossil-Based Performance Polymers

Engineering Proceedings, 2023
Graft copolymerization of acrylic acid onto starch can provide renewable alternatives for current applications of water-soluble performance polymers from fossil resources.
Inge Willem Noordergraaf, Judy R. Witono, Hero J. Heeres   +2 more
doaj   +1 more source

Topological and Algebraic Properties of Chernoff Information between Gaussian Graphs

, 2018
In this paper, we want to find out the determining factors of Chernoff information in distinguishing a set of Gaussian graphs. We find that Chernoff information of two Gaussian graphs can be determined by the generalized eigenvalues of their covariance ...
Li, Binglin, Wang, Yue, Wei, Shuangqing, Yuan, Jian   +3 more
core   +1 more source

Transplantation stimulates interstitial cell migration in hydra [PDF]

, 1990
Migration of interstitial cells and nerve cell precursors was analyzed in Hydra magnipapillata and Hydra vulgaris (formerly Hydra attenuata). Axial grafts were made between [3H]thymidine-labeled donor and unlabeled host tissue. Migration of labeled cells
Bosch, Bosch, Campbell, Campbell, David, Fujisawa, Heimfeld, Heimfeld, Herlands, Tardent, Vögeli   +10 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Physio-Anatomical Study of Polyploid Watermelon Grafted by Different Methods

Agronomy, 2021
Watermelon is one of the most desirable vegetable crops in the world. Recently, grafting is common in watermelons worldwide, but not all grafting methods are compatible with polyploids. In this study, diploid, triploid, and tetraploid from one watermelon
Mohamed Omar Kaseb, Muhammad Jawad Umer, Eftekhar Mahmud, Muhammad Anees, Weinan Diao, Pingli Yuan, Hongju Zhu, Shengjie Zhao, Xuqiang Lu, Nan He, Eman El-remaly, Wenge Liu   +11 more
doaj   +1 more source

Grafting Methods for Watermelon Production [PDF]

HortScience, 2008
Vegetable grafting is most common in European and Asian countries where crop rotation is no longer an option and available land is under intense use. Grafting is an alternative approach to reduce crop damage resulting from soilborne pathogens and increase plant abiotic stress tolerance, which increases crop production.
Richard L. Hassell, Frederic Memmott, Dean G. Liere   +2 more
openaire   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Serial Injections of Cryopreserved Fat at −196°C for Tissue Rejuvenation, Scar Treatment, and Volume Augmentation

Plastic and Reconstructive Surgery, Global Open, 2018
Background:. Fat grafting has become popular since the first report of structural fat grafting in 2001. Fat grafting is effective not only for volume augmentation but also for tissue revitalization.
Masanori Ohashi, MD, Akihiko Chiba, MD, Hirokazu Nakai, MD, Etsu Fukuda, MD, Takao Higuchi, MD   +4 more
doaj   +1 more source

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source