Results 51 to 60 of about 13,349 (202)

“Why?”: C. Wright Mills on the Spirit of the Classical Sociological Tradition and Positivist Versus Critical Sociology

Sociology Lens, EarlyView.
ABSTRACT Despite their very diverse interests, the classical sociological thinkers were concerned with analyzing the dramatic social transformations in the wake of colonialism, slavery, and modern industrial capitalism as well as the multiple revolutions, particularly in relation to the new forms of social inequalities and power disparities.
Zaheer Baber
wiley   +1 more source

Absence of Grail promotes CD8+ T cell anti-tumour activity

Nature Communications, 2017
Grail is an E3 ubiquitin ligase that inhibits T-cell receptor signalling in CD4+ T cells. Here the authors show Grail also limits IL-21 receptor expression and function in CD8+ T cells, is overactive in these cells in patients with lymphoma, and promotes
Cara Haymaker, Yi Yang, Junmei Wang, Qiang Zou, Anupama Sahoo, Andrei Alekseev, Divyendu Singh, Krit Ritthipichai, Yared Hailemichael, Oanh N. Hoang, Hong Qin, Kimberly S. Schluns, Tiejun Wang, Willem W. Overwijk, Shao-Cong Sun, Chantale Bernatchez, Larry W. Kwak, Sattva S. Neelapu, Roza Nurieva   +18 more
doaj   +1 more source

Make Social Media Social Again: How Platform Interoperability Can Fix Social Media and Future‐Proof Democracy

Journal of Management Studies, EarlyView.
Abstract This essay argues that social media document (rather than fuel) the decline of political democracy while helping revive organizational democracy, including through ‘decentralized autonomous organizations’ (DAOs). Yet, despite giving everyone a voice and the ability to organize across borders, social media could over‐concentrate power if, in ...
J.P. Vergne
wiley   +1 more source

Author Correction: A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection

Nature Communications, 2022
Matthew H. Larson, Wenying Pan, Hyunsung John Kim, Ruth E. Mauntz, Sarah M. Stuart, Monica Pimentel, Yiqi Zhou, Per Knudsgaard, Vasiliki Demas, Alexander M. Aravanis, Arash Jamshidi   +10 more
doaj   +1 more source

Alternative endpoints to mortality in cancer screening trials

Molecular Oncology
The reliance on mortality endpoints in cancer screening trials is not always compatible with the need to accelerate progress in outcomes for patient and public benefit.
Sir Harpal Kumar
doaj   +1 more source

Theodor Steinbüchel's Great Figures of Christian Humanism

Modern Theology, EarlyView.
Abstract Theodor Steinbüchel (1888–1949) offers a study of eight figures in Western history who may be regarded as gestalts of Christian Humanism. He argued that none of these eight figures will ever return in the same way, but since there was an eternal conception of Christianity to which their ethos gave human form, each of these gestalts can be ...
Tracey Rowland
wiley   +1 more source

Physics-based and data-driven hybrid modeling in manufacturing: a review

Production and Manufacturing Research: An Open Access Journal
Manufacturing, an industry set in the physical world, is undergoing its digital transformation, also known as the fourth industrial revolution. Sensors, connectivity, and platforms provide unprecedented access to quantify the quality and diversity of ...
Sathish Kasilingam, Ruoyu Yang, Shubhendu Kumar Singh, Mojtaba A. Farahani, Rahul Rai, Thorsten Wuest   +5 more
doaj   +1 more source

The new Holy Grail

BMJ, 1998
E was an 87 year old man with chronic bronchitis and some deafness. He presented yet again with increasing dyspnoea. I listened to his chest for the expected wheeze. “Haven't really got much better Doc, started the steroids like you said and doubled my inhalers.” Then I noted in the background the irregular, rapid pulse.
openaire   +3 more sources

Signaling Mutations Negate the Favorable Impact of NPM1 Mutations in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With VEN/HMA

American Journal of Hematology, Volume 101, Issue 9, Page 2246-2257, September 2026.
ABSTRACT Frameshift mutations in exon 12 of nucleophosmin 1 (NPM1 mut) are among the most common mutations in acute myeloid leukemia (AML) and have historically been considered favorable‐risk in the absence of FLT3‐ITD. In the European LeukemiaNet (ELN) 2024 risk‐classification for patients treated with hypomethylating agents plus venetoclax (HMA + VEN)
Fieke W. Hoff, Joshua F. Zeidner, Geeta Torlapati, Deedra Nicolet, Krzysztof Mrózek, Ying Huang, Alexander Li, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L. Lin, Maria R. Baer, Vu H. Duong, William G. Blum, Martha L. Arellano, Wendy Stock, Olatoyosi Odenike, Rebecca L. Olin, Catherine C. Smith, Gary J. Schiller, Emily K. Curran, Onyee Chan, Christine McMahon, Michael Hochman, Kieran Sahasrabudhe, Charles Foucar, Jesus Gonzalez‐Lugo, Brittany Knick Ragon, Shivani V. Handa, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja G. Marcus, Leonard Rosenberg, Brian J. Druker, Ross L. Levine, Amy Burd, Ashley O. Yocum, Uma M. Borate, Alice S. Mims, Ann‐Katrin Eisfeld, John C. Byrd, Yazan F. Madanat   +44 more
wiley   +1 more source

Community and Communion in the Quest of the Holy Grail [PDF]

HyperCultura, 2015
: In this article the author intends to analyze to what extent the Holy Grail, which may be regarded as a symbol for the Holy Communion, can be considered the basis for creating and preserving a community in the Quest of the Holy Grail (La Queste del ...
Monica Ruset Oancă
doaj