Results 71 to 80 of about 13,349 (202)
Background The added benefits of a multi-cancer early detection (MCED) test among individuals with multiple risk factors will help policy decision-makers allocate limited healthcare resources.
Ashley Kim +7 more
doaj +1 more source
The strengths of formal Bayesian chronological modelling are restated, combining as it does knowledge of the archaeology with the radiocarbon dating of carefully chosen samples of known taphonomy in association with diagnostic material culture.
Eszter Banffy +10 more
doaj +1 more source
MYC in Oncogenesis and Therapeutic Implications
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang +5 more
wiley +1 more source
Resumen El propósito de este trabajo es analizar las apariciones del Grial y de las espadas maravillosas en los episodios conservados en la versión toscana de La Queste del Saint Graal, La Inchiesta del San Gradale (siglo XIV), ya que desempeñan una ...
Antonio Contreras Martín
doaj +1 more source
Targeting CD148 for Antithrombotic Therapy: Functional and Molecular Evaluation of AKB‐9778
ABSTRACT CD148 is the primary receptor‐type protein tyrosine phosphatase (PTP) regulating platelet activation, and its inhibition has been proposed as a novel anti‐thrombotic strategy with potentially lower bleeding risk than current therapies. However, selective and potent inhibitors of CD148 are currently lacking.
Lina El Badaoui +3 more
wiley +1 more source
Accuracy of occurrence and abundance estimates from insect metabarcoding
Abstract DNA metabarcoding—high‐throughput sequencing of barcode regions from bulk samples—has become a key tool for insect biodiversity assessment. Yet, how methodological choices affect the accuracy of metabarcoding data remains insufficiently explored. In this paper, we ask: (1) How does the lysis method (non‐destructive lysis vs.
Ela Iwaszkiewicz‐Eggebrecht +12 more
wiley +1 more source
THE ROUTE OF THE HOLY GRAIL: FROM SAN JUAN DE LA PEÑA TO VALENCIA. THE STRUCTURING OF A TERRITORY BASED ON ORAL TRADITION [PDF]
The Route of the Holy Grail was presented FITUR 2017 (Madrid, January 2017) by the Agència Valenciana del Turisme. It involves structuring a routethat connects the communities of Aragon and Valencia by use of touristic description that encompasses ...
Ana Mafé García
doaj
The New Cycle of the Grail in the 20th Century and its Mythical Origin
The myth of the Grail has been formed in literature. It has been given birth by Chretien de Troyes and was influenced by holly texts. At first, the Grail is not sacred but it appears in a mysterious chain of events and gives birth to a myth which will be
آندیا عبائی +1 more
doaj
Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study
Protein-truncating variants (PTVs) are predicted to significantly affect a gene’s function and, thus, human traits. Here, DeBoever et al. systematically analyze PTVs in more than 300,000 individuals across 135 phenotypes and identify 27 associations ...
Christopher DeBoever +10 more
doaj +1 more source

