Results 51 to 60 of about 132,770 (306)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Review on Grain Refinement of Metallic Materials to Regulate Cellular Behavior

Metals, 2022
Metallic materials have been widely used as orthopedic implants in clinics for their good mechanical, physical, and chemical properties, but their slow osseointegration rate is still one of the main issues causing implantation failure.
Yingjian Gu, Run Huang, Yufei Hao
doaj   +1 more source

The Influence of the effect of solute on the thermodynamic driving force on grain refinement of Al alloys [PDF]

, 2014
Grain refinement is known to be strongly affected by the solute in cast alloys. Addition of some solute can reduce grain size considerably while others have a limited effect.
A. Cibula, A.L. Greer, A.T. Dinsdale, B.S. Murty, D.A. Porter, D.G. McCartney, D.H. StJohn, D.H. StJohn, D.H. StJohn, Dong Qiu, E Clouet, F. Wang, F. Wang, F. Wang, Feng Wang, H. Feufel, H. Fredriksson, I. Maxwell, I. Ohnuma, J. Grobner, J. Grobner, J.A. Dantzig, J.A. Marcantonio, J.A. Spittle, J.H. Perepezko, J.O. Andersson, John A. Taylor, K. Keslioglu, L. Battezzati, M. Glicksman, M. Gunduz, M. Gunduz, M. Johnsson, M. Johnsson, M. Johnsson, M. Qian, M.A. Easton, M.A. Easton, M.A. Easton, M.A. Easton, M.A. Easton, M.D. Eborall, M.J. Bermingham, M.M. Guzowski, Mark A. Easton, Ming-Xing Zhang, N. Eustathopoulos, N. Marasli, N. Saunders, N. Saunders, N. Saunders, P. Liang, P.S. Mohanty, S. Engin, S.-W. Chen, S.L. Chen, T. Wang, T.E. Quested, U.R. Kattner, V.T. Witusiewicz, W. Kurz, Zhi-Lin Liu   +61 more
core   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Grain refinement of AZ91D alloy by intensive melt shearing and its persistence after remelting and isothermal holding [PDF]

China Foundry, 2013
Intensive melt shearing has a significant grain refining effect on some light alloys. However, the persistence of the grain refining effect during isothermal holding and remelting is still unclear, although it is very important for the practical ...
Zuo Yubo, Fan Zhongyun, Cui Jianzhong
doaj  

Effects of grain refinement on cast structure and tensile properties of superalloy K4169 at high pouring temperature [PDF]

China Foundry, 2016
In order to improve the filling ability of large complex thin wall castings, the pouring temperature should be increased, but this will result in the grain coarsening. To overcome this problem, two kinds of grain refiners of Co-Fe-Nb and Cr-Fe-Nb ternary
Zi-qi Jie, Jun Zhang, Tai-wen Huang
doaj   +1 more source

Zjemňování zrna protlačované hořčíkové slitiny AZ31 procesem Ecap [PDF]

, 2017
Extruded Mg – 3%Al – 1% Zn (AZ31) magnesium alloy was subjected to ECAP (Equal Channel Angular Pressing) processing at 523 K (250 °C). At the processing temperature of 523 K, fine grains with the average grain size of 2 – 3 μm are formed as a result of ...
Hilšer, Ondřej, Krejčí, Lucie, Rusz, Stanislav, Špalek, František   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Effect of grain refinement on the stress rupture property of K447A alloy

Journal of Aeronautical Materials
Grain refinement can effectively enhance mechanical properties of materials at low and medium temperatures，however，it may weaken the stress rupture property above the equicohesive temperature. To study the effect of grain refinement on the stress rupture
HU Pinpin, DING Ning, WANG Yue, LI Yanjia, ZHANG Mingjun, XIAO Chengbo, HE Jinshan, WANG Xitao   +7 more
doaj   +1 more source

Taguchi Approach for Optimization of Parameters that Effect Grain Size of Cast A357 Alloy

Archives of Foundry Engineering, 2017
Grain refining and modification are common foundry practice for improving properties of cast Al-Si alloys. In general, these types of treatments provide better fluidity, decreased porosity, higher yield strength and ductility. However, in practice, there
Çolak M., Dışpınar D.
doaj   +1 more source