Results 41 to 50 of about 188,621 (289)

Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji, Marcello Moccia, Alessia Bianchi, Charmaine Yam, Weaam Hamed, Suraya Mohamud, Alan J. Thompson, Frederik Barkhof, Ahmed T. Toosy, Olga Ciccarelli   +9 more
wiley   +1 more source

Dissecting the Genetic Basis of Grain Size and Weight in Barley (Hordeum vulgare L.) by QTL and Comparative Genetic Analyses

Frontiers in Plant Science, 2019
Grain size and weight are crucial components of barley yield and quality and are the target characteristics of domestication and modern breeding. Despite this, little is known about the genetic and molecular mechanisms of grain size and weight in barley.
Qifei Wang, Genlou Sun, Xifeng Ren, Binbin Du, Yun Cheng, Yixiang Wang, Chengdao Li, Dongfa Sun, Dongfa Sun   +8 more
doaj   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source

Preparation of MnO2 from manganese natural ore [PDF]

Carbon: Science and Technology, 2017
Owing to wide applications of manganese oxides in waste water treatment, fertilizers, catalysis, sensors, super capacitors and rechargeable batteries has got novel attention worldwide.
S. K. Sinha, Hari Mahto, Md. Shahid, D. Shikha, S. Murugesan, E. Mohandas   +5 more
doaj  

Numerical and Experimental Investigation of the Influence of Growth Restriction on Grain Size in Binary Cu Alloys

Metals, 2017
Grain refinement by elemental addition has been extensively investigated within the last decades in Al or Mg alloys. In contrast, in the Cu system, the role of solute on grain size is less investigated.
Andreas Cziegler, Olga Geraseva, Peter Schumacher   +2 more
doaj   +1 more source

Prediction of Grain Size in Cast Aluminum Alloys

Crystals, 2022
Grain refinement of cast alloys, especially aluminum–silicon and magnesium-based alloys, is an effective approach to improve the strength of alloys. Grain size is the most representative parameter used to characterize grain refinement in the industry ...
Shuai Ma, Zhibo Zhang, Zhuming Huang, Dongfu Song, Yiwang Jia, Nan Zhou, Kai Wang, Kaihong Zheng, Huijing Du   +8 more
doaj   +1 more source

Ageism in Rheumatology: The Health Care Professional's Perspective

Arthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

Critical grain sizes and generalized flow stress - grain size dependence

, 2013
The generalized eguation that describes the yield stress dependence upon the grain size in the wide range of grain sizes has been obtained. There are two critical grain sizes that corresponds to the changes in strengthening mechanism. The equation includes Hall - Petch relation in the range of d>dcr1.
Firstov, S. A., Rogul, T. R., Shut, O. A.   +2 more
openaire   +2 more sources

Effect of grain size and grain size distribution on slip dynamics: An experimental analysis

Tectonophysics, 2020
Abstract When faults form and slip they produce granular wear material that accommodates most of the strain. We investigate the effect of grain size and grain size distribution on slip dynamics by using sheared elliptical acrylic discs as a fault gouge proxy.
Randolph-Flagg, Jeremy, Reber, Jacqueline   +1 more
openaire   +4 more sources

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

Arthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond YH Yap, KL Lee, Philip H Li, Iris YK Tang, Chak Sing Lau, Shirley CW Chan   +6 more
wiley   +1 more source