Results 11 to 20 of about 575,807 (162)

Genome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014

Antimicrobial Resistance and Infection Control, 2018
Background By using whole genome sequence data we aimed at describing a population snapshot of carbapenemase-producing K. pneumoniae isolated from hospitalized patients in Germany between 2008 and 2014.
Laura Becker, Martin Kaase, Yvonne Pfeifer, Stephan Fuchs, Annicka Reuss, Anja von Laer, Muna Abu Sin, Miriam Korte-Berwanger, Sören Gatermann, Guido Werner   +9 more
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A recurrent and transesophageal echocardiography–associated outbreak of extended-spectrum β-lactamase–producing Enterobacter cloacae complex in cardiac surgery patients

Antimicrobial Resistance and Infection Control, 2019
Background We report a recurrent outbreak of postoperative infections with extended-spectrum β-lactamase (ESBL)–producing E. cloacae complex in cardiac surgery patients, describe the outbreak investigation and highlight the infection control measures ...
Tom Van Maerken, Els De Brabandere, Audrey Noël, Liselotte Coorevits, Pascal De Waegemaeker, Raina Ablorh, Stefaan Bouchez, Ingrid Herck, Harlinde Peperstraete, Pierre Bogaerts, Bruno Verhasselt, Youri Glupczynski, Jerina Boelens, Isabel Leroux-Roels   +13 more
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IS26-Mediated Transfer of blaNDM–1 as the Main Route of Resistance Transmission During a Polyclonal, Multispecies Outbreak in a German Hospital

Frontiers in Microbiology, 2019
One of the most demanding challenges in infection control is the worldwide dissemination of multidrug-resistant (MDR) bacteria in clinical settings. Especially the increasing prevalence of carbapenemase producing Gram-negative pathogens poses an urgent ...
Robert E. Weber, Michael Pietsch, Andre Frühauf, Yvonne Pfeifer, Maria Martin, Dirk Luft, Sören Gatermann, Niels Pfennigwerth, Martin Kaase, Guido Werner, Stephan Fuchs   +10 more
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Environmental microbial communications in gram-positive and gram-negative bacteria [PDF]

Global Journal of Environmental Science and Management, 2023
Microorganisms are present in nature and shape an enormous a half of our micro- and macro-environment. Quorum sensing is the process of intercellular conversation that enables microbes to perceive their surroundings and change their behaviour, allowing ...
P. Srikanth, D. Sivakumar, J. Nouri
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In Vitro Activity of Cefiderocol against Clinical Gram-Negative Isolates Originating from Germany in 2016/17

Antibiotics, 2023
Antimicrobial resistance poses a global threat to public health. Of great concern are Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales with resistance to carbapenems or third-generation cephalosporins. The aim of the present study was
Esther Wohlfarth, Michael Kresken, Fabian Deuchert, Sören G. Gatermann, Yvonne Pfeifer, Niels Pfennigwerth, Harald Seifert, Paul G. Higgins, Guido Werner, Study Group ‘Antimicrobial Resistance‘ of the Paul Ehrlich Society for Infection Therapy   +9 more
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Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination

Antibiotics, 2020
Antimicrobial resistance (AMR) is one of the most prominent public health threats. AMR genes localized on plasmids can be easily transferred between bacterial isolates by horizontal gene transfer, thereby contributing to the spread of AMR.
Bas Berbers, Pieter-Jan Ceyssens, Pierre Bogaerts, Kevin Vanneste, Nancy H. C. Roosens, Kathleen Marchal, Sigrid C. J. De Keersmaecker   +6 more
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In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia

Frontiers in Cellular and Infection Microbiology, 2023
Multidrug-resistant (MDR) Pseudomonas aeruginosa has been declared a serious threat by the United States Centers for Disease Control and Prevention. Here, we used whole genome sequencing (WGS) to investigate recurrent P. aeruginosa bloodstream infections
Natasha Spottiswoode, Samantha Hao, Samantha Hao, Estella Sanchez-Guerrero, Angela M. Detweiler, Honey Mekonen, Norma Neff, Henriette Macmillan, Brian S. Schwartz, Joanne Engel, Joseph L. DeRisi, Joseph L. DeRisi, Steven A. Miller, Steven A. Miller, Charles R. Langelier, Charles R. Langelier   +15 more
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Molecular surveillance of carbapenemase-producing Pseudomonas aeruginosa at three medical centres in Cologne, Germany

Antimicrobial Resistance and Infection Control, 2019
Background Pseudomonas aeruginosa is a common pathogen causing hospital-acquired infections. Carbapenem resistance in P. aeruginosa is either mediated via a combination of efflux pumps, AmpC overexpression, and porin loss, or through an acquired ...
Elena Schäfer, Monika Malecki, Carlos J. Tellez-Castillo, Niels Pfennigwerth, Lennart Marlinghaus, Paul G. Higgins, Frauke Mattner, Andreas F. Wendel   +7 more
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Comparison of testing methods assessing the in vitro efficacy of the combination of aztreonam with avibactam on multidrug-resistant Gram-negative bacilli

Annals of Clinical Microbiology and Antimicrobials
Background Aztreonam-avibactam (ATM-AVI) combination shows promising effectiveness on most carbapenemase-producing Gram-negatives, yet standardized antibiotic susceptibility testing (AST) methods for evaluating the combination in clinical laboratories is
Corentin Deckers, Florian Bélik, Olivier Denis, Pierre Bogaerts, Isabel Montesinos, Catherine Berhin, Warda Bouchahrouf, Martin Hoebeke, Stephanie Evrard, Nicolas Gilliard, Merve Okur, Te-Din Huang   +11 more
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Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

International Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert, Simon Brinkwirth, Niels Pfennigwerth, Sebastian Haller, Lena Sophie Fritsch, Tim Eckmanns, Guido Werner, Sören Gatermann, Jörg B. Hans   +8 more
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