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GBP1 recruitment to actin-rich pedestals induced by extracellular Gram-negative bacteria promotes pyroptosis

open access: yes
Bennison DJ   +13 more
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Gram-Negative Bacteria

2011
Aeromonas species are gram-negative anaerobic rods found in fresh water lakes and streams. They have also been recovered from chlorinated tap water, including hospital water supplies. Aeromonas infections of freshwater traumatic wounds cause a characteristic clinical picture indistinguishable from group A streptococcal infection in normal hosts ...
Marc E. Grossman   +3 more
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Non-fermentative Gram-negative bacteria

International Journal of Antimicrobial Agents, 2007
Over the past decade, non-fermenting Gram-negative bacteria have emerged as important opportunistic pathogens in the increasing population of patients who are immunocompromised by their disease or medical treatment. These bacteria are assisted by their ubiquitous distribution in the environment and have a propensity for multiple, intrinsic or acquired ...
D A, Enoch, C I, Birkett, H A, Ludlam
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Gram-Negative Bacteria

2001
The cell wall of Gram-negative bacteria has a very distinctive layered look under the electron microscope and is dramatically different from the Gram-positive cell wall. The inner layer consists of a thin peptidoglycan layer; the outer layer or outer membrane is a protein containing bilayer.
Robert P. Rapp, Kenneth E. Record
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Leukotoxins of gram-negative bacteria

Veterinary Microbiology, 2002
Leukotoxins are a group of exotoxins that produce their primary toxic effects against leukocytes, especially polymorphonuclear cells (PMNs). Leukotoxins include a variety of chemicals ranging from 9,10-epoxy 12-octadecenoate, a fatty acid derivative secreted by leukocytes themselves, to proteins such as RTX (repeats in toxin).
Sanjeev Kumar, Narayanan   +3 more
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Antibiotic uptake into gram-negative bacteria

European Journal of Clinical Microbiology & Infectious Diseases, 1988
Antibiotics taken up into gram-negative bacteria face two major diffusion barriers, the outer and cytoplasmic membranes. Of these, the former has been most studied and is discussed in detail here. Evidence from antibiotic MIC studies on porin-deficient mutants compared with their porin-sufficient parent strains has provided strong support for the ...
R E, Hancock, A, Bell
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Resistance mechanisms in Gram-negative bacteria

Medicina Intensiva (English Edition), 2022
Enterobacterales resistant to carbapenems or producing extended-spectrum β-lactamases (ESBL) and non-fermenters resistant to carbapenems present resistance to many of the antimicrobials commonly used in clinical practice, and have been recognized by the World Health Organization as a critical priority for the development of new antimicrobials.
Lepe, José A.   +1 more
openaire   +3 more sources

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