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How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Protein Secretion by Gram-negative Bacteria
International ...
D'Enfert, Christophe +3 more
openaire +3 more sources
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The “other” gram-negative bacteria in mastitis [PDF]
Gram-negative bacteria are an important cause of bovine mastitis throughout the world. With the advance of our understanding of the main risk factors for classic contagious bacteria such Streptococcus agalactiae and Staphylococcus aureus, we have ...
A. Gurjar +13 more
core +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Introduction: Resulting from an analysis of an outbreak of carbapenem-resistant Pseudomonas (P.) aeruginosa, the siphons of washbasins in patient rooms were identified as source of colonizations and/or infections.
Torsten Stein +4 more
doaj +1 more source
Anhydrobiotic Engineering of Gram-Negative Bacteria [PDF]
ABSTRACT Anhydrobiotic engineering aims to improve desiccation tolerance in living organisms by adopting the strategies of anhydrobiosis. This was achieved for Escherichia coli and Pseudomonas putida by osmotic induction of intracellular trehalose synthesis and by drying from ...
A, García De Castro +3 more
openaire +2 more sources
Regulation of innate and adaptive immune responses by Gram-positive and Gram-negative bacteria [PDF]
Bacteria are classified as Gram-positive or Gram-negative, depending on their cell wall structure. The role of the bacterial cell wall in immune regulation is the focus of the current work.
Martner, Anna
core
Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2 [PDF]
Innate immune recognition is the first line of host defense against invading microorganisms. It is a based on the detection, by pattern recognition receptors (PRRs), of invariant molecular signatures that are unique to microorganisms.
Alain Vercellone +26 more
core +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source

