Results 261 to 270 of about 430,389 (345)

CuH‐Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination

open access: yesChemistryEurope, EarlyView.
The CuH‐catalyzed stereodivergent hydroamination through asymmetric desymmetrization of cyclobutenes has been achieved, yielding a range of trisubstituted aminocyclobutanes with excellent results. A series of subsequent transformations, including the first asymmetric synthesis of two pharmaceutically active molecules, have been realized, and density ...
Xiang Lei   +8 more
wiley   +1 more source

Epidemiology and Clinical Outcome of Common Multi-drug Resistant Gram-negative Bacterial Infections in a Network of Hospitals in India (IMPRES): A Multicenter Intensive Care Unit-based Prospective Clinical Study. [PDF]

open access: yesIndian J Crit Care Med
Das SK   +32 more
europepmc   +1 more source

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

open access: yesChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima   +2 more
wiley   +1 more source

Development of novel antimicrobials with engineered endolysin LysECD7-SMAP to combat Gram-negative bacterial infections. [PDF]

open access: yesJ Biomed Sci
Vasina DV   +29 more
europepmc   +1 more source

Synthetic Studies towards Darobactin A

open access: yesChemistry – A European Journal, EarlyView.
The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Till Steiner   +4 more
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Current Practice of Antimicrobial Prophylaxis to Prevent Gram-Negative Bacterial Infection in High-Risk Haematology Patients: Results from an International Survey

open access: green
Jannik Stemler   +8 more
openalex   +1 more source

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