Multidrug-resistant (MDR) Gram-negative bacteria are the top-priority pathogens to be eradicated. Drug repurposing (e.g., the use of non-antibiotics to treat bacterial infections) may be helpful to overcome the limitations of current antibiotics ...
Hyejin Cho, Kwang-sun Kim
doaj +1 more source
Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou [PDF]
AIM: To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs.
Li Zhang +6 more
doaj +1 more source
Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections [PDF]
Imipenem/cilastatin/relebactam (Recarbrio™) is an intravenously administered combination of the carbapenem imipenem, the renal dehydropeptidase-I inhibitor cilastatin, and the novel β-lactamase inhibitor relebactam. Relebactam is a potent inhibitor of class A and class C β-lactamases, conferring imipenem activity against many imipenem-nonsusceptible ...
openaire +3 more sources
Efficacy of Disinfectants on Bacteria; Case Study of Isfahan Hospitals
Aims: The internal unit and ICU of hospitals are a suitable environment for growing of bacteria such as Staphylococcus epidermidis, Pseudomonas and Acinetobacters.
Nourbakhsh F.*
doaj
Ocular infections can be medical emergencies that result in permanent visual impairment or blindness and loss of quality of life. Bacteria are a major cause of ocular infections.
Roger A. Astley +7 more
doaj +1 more source
Treatment and control of invasive Gram-negative bacterial infection in eight hospitals across sub-Saharan Africa: a cross-sectional study [PDF]
Alexander M. Aiken +18 more
openalex +2 more sources
A Randomized, Open-Label, Non-inferiority Clinical Trial Assessing 7 Versus 14 Days of Antimicrobial Therapy for Severe Multidrug-Resistant Gram-Negative Bacterial Infections: The OPTIMISE Trial Protocol [PDF]
Beatriz Arns +14 more
openalex +1 more source
Immunotherapy in gram-negative bacterial infections.
Endotoxins are responsible for initiation of septic shock which increases the number of fatalities in Gram-negative bacteremia among hospital patients. The mortality from septic shock is still high despite recent developments in antibiotic therapy because antibiotics are unable to decrease the level of free lipopolysaccharide in the blood stream ...
openaire +3 more sources
Immunological changes associated with post-surgical gram-negative bacterial infections
Objective: Post-surgical bacterial infections provoke immune responses mediated by various cytokines. This study aimed to assess immunological changes by measuring serum levels of IL-2, IL-7, IL-10, and IL-17 in post-surgical patients with bacterial ...
Massar Dohan +2 more
doaj +1 more source
The gradual rise of multidrug resistant micro-organisms is a national concern for all health care providers. Linezolid belongs to the oxazolidinone class of antimicrobials.
Satish Chandel +3 more
doaj +1 more source

