Results 41 to 50 of about 272,499 (204)

Repurposing of Ciclopirox to Overcome the Limitations of Zidovudine (Azidothymidine) against Multidrug-Resistant Gram-Negative Bacteria

open access: yesPharmaceutics, 2022
Multidrug-resistant (MDR) Gram-negative bacteria are the top-priority pathogens to be eradicated. Drug repurposing (e.g., the use of non-antibiotics to treat bacterial infections) may be helpful to overcome the limitations of current antibiotics ...
Hyejin Cho, Kwang-sun Kim
doaj   +1 more source

Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou [PDF]

open access: yesInternational Journal of Ophthalmology
AIM: To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs.
Li Zhang   +6 more
doaj   +1 more source

Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections [PDF]

open access: yesDrugs, 2021
Imipenem/cilastatin/relebactam (Recarbrio™) is an intravenously administered combination of the carbapenem imipenem, the renal dehydropeptidase-I inhibitor cilastatin, and the novel β-lactamase inhibitor relebactam. Relebactam is a potent inhibitor of class A and class C β-lactamases, conferring imipenem activity against many imipenem-nonsusceptible ...
openaire   +3 more sources

Efficacy of Disinfectants on Bacteria; Case Study of Isfahan Hospitals

open access: yesInternational Archives of Health Sciences, 2016
Aims: The internal unit and ICU of hospitals are a suitable environment for growing of bacteria such as Staphylococcus epidermidis, Pseudomonas and Acinetobacters.
Nourbakhsh F.*
doaj  

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

open access: yesMicroorganisms, 2023
Ocular infections can be medical emergencies that result in permanent visual impairment or blindness and loss of quality of life. Bacteria are a major cause of ocular infections.
Roger A. Astley   +7 more
doaj   +1 more source

Treatment and control of invasive Gram-negative bacterial infection in eight hospitals across sub-Saharan Africa: a cross-sectional study [PDF]

open access: green, 2022
Alexander M. Aiken   +18 more
openalex   +2 more sources

A Randomized, Open-Label, Non-inferiority Clinical Trial Assessing 7 Versus 14 Days of Antimicrobial Therapy for Severe Multidrug-Resistant Gram-Negative Bacterial Infections: The OPTIMISE Trial Protocol [PDF]

open access: gold, 2023
Beatriz Arns   +14 more
openalex   +1 more source

Immunotherapy in gram-negative bacterial infections.

open access: yesActa Biochimica Polonica, 1995
Endotoxins are responsible for initiation of septic shock which increases the number of fatalities in Gram-negative bacteremia among hospital patients. The mortality from septic shock is still high despite recent developments in antibiotic therapy because antibiotics are unable to decrease the level of free lipopolysaccharide in the blood stream ...
openaire   +3 more sources

Immunological changes associated with post-surgical gram-negative bacterial infections

open access: yesBabcock University Medical Journal
Objective: Post-surgical bacterial infections provoke immune responses mediated by various cytokines. This study aimed to assess immunological changes by measuring serum levels of IL-2, IL-7, IL-10, and IL-17 in post-surgical patients with bacterial ...
Massar Dohan   +2 more
doaj   +1 more source

Linezolid Resistance against Gram Positive Bacteria Isolated from Blood Stream Infections: A Challenging Threat

open access: yesJournal of Pure and Applied Microbiology, 2022
The gradual rise of multidrug resistant micro-organisms is a national concern for all health care providers. Linezolid belongs to the oxazolidinone class of antimicrobials.
Satish Chandel   +3 more
doaj   +1 more source

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